5-HT1E: Small Molecules and Peptides
5-HT1E is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1E is mediated by G proteins that inhibit adenylate cyclase activity. The 5-HT1E receptor is found mainly in the cerebral cortex. Abnormal function of the serotonergic system has been implicated in a variety of neurologic and psychiatric diseases. 5-HT1E may play a role in these diseases.
5 results for "5-HT1E Small Molecules and Peptides" in Products
5 results for "5-HT1E Small Molecules and Peptides" in Products
5-HT1E: Small Molecules and Peptides
5-HT1E is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1E is mediated by G proteins that inhibit adenylate cyclase activity. The 5-HT1E receptor is found mainly in the cerebral cortex. Abnormal function of the serotonergic system has been implicated in a variety of neurologic and psychiatric diseases. 5-HT1E may play a role in these diseases.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist
| Chemical Name: | 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Purity: | ≥98% (HPLC) |
Selective α2 antagonist
| Chemical Name: | 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride |
| Purity: | ≥98% (HPLC) |
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | ICI 204,636 |
| Chemical Name: | 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
| Purity: | ≥98% (HPLC) |
High affinity D2 antagonist
| Chemical Name: | 3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole |
| Purity: | ≥98% (HPLC) |
