Yohimbine hydrochloride
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Selective α2 antagonist |
Chemical Name: | 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 390.91 |
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Citations for Yohimbine hydrochloride (21)
Citations are publications that use Bio-Techne products. Selected citations for Yohimbine hydrochloride include:
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Hirschberg et al.
(2017)
Functional dichotomy in spinal- vs prefrontal-projecting locus coeruleus modules splits descending noradrenergic analgesia from ascending aversion and anxiety in rats.
Elife.
6
PMID: 29027903 -
Delaney and Crane
(2016)
Presynaptic GABAB receptors reduce transmission at parabrachial synapses in the lateral central amygdala by inhibiting N-type calcium channels.
Sci Rep.
6:19255
PMID: 26755335 -
Kastman et al.
(2016)
Nucleus incertus Orexin2 receptors mediate alcohol seeking in rats
Neuropharmacology.
110:82
PMID: 27395787 -
Scardochio et al.
(2015)
The Effects of Electrical and Optical Stimulation of Midbrain DArgic Neurons on Rat 50-kHz Ultrasonic Vocalizations.
Front Behav Neurosci.
9:331
PMID: 26696851 -
Gazarini et al.
(2015)
PTSD-like memory generated through enhanced noradrenergic activity is mitigated by a dual step pharmacological intervention targeting its reconsolidation.
Int J Neuropsychopharmacol.
18
PMID: 25539509 -
Dudek et al.
(2015)
A Comparison of the Anorectic Effect and Safety of the Alpha2-Adrenoceptor Ligands guanf. and Yohimbine in Rats with Diet-Induced Obesity.
PLoS One.
10:e0141327
PMID: 26506439 -
Soty et al.
(2015)
A gut-brain neural circuit controlled by intestinal gluconeogenesis is crucial in metabolic health.
Psychopharmacology (Berl).
4:106
PMID: 25685698 -
Phelps et al.
(2015)
Psychopharmacological characterisation of the successive negative contrast effect in rats.
Proc Natl Acad Sci U S A.
232:2697
PMID: 25791190 -
Drake et al.
(2014)
The degree of acute descending control of spinal nociception in an area of primary hyperalgesia is dependent on the peripheral domain of afferent input.
J Physiol.
592:3611
PMID: 24879873 -
Costello et al.
(2014)
Comparison of the reinforcing properties of nicotine and cigarette smoke extract in rats.
Neuropsychopharmacology.
39:1843
PMID: 24513971 -
Ciccocioppo et al.
(2014)
Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat.
Neuropsychopharmacology.
39:2601
PMID: 24863033 -
Corcoran et al.
(2014)
Dual effects of 5-HT(1a) receptor activation on breathing in neonatal mice.
Mol Metab.
34:51
PMID: 24381267 -
Yuen et al.
(2014)
Synergistic regulation of glutamatergic transmission by serotonin and NE reuptake inhibitors in prefrontal cortical neurons.
J Biol Chem.
289:25177
PMID: 25056951 -
Mondal et al.
(2013)
Mechanism of ghrelin-induced gastric contractions in Suncus murinus (house musk shrew): involvement of intrinsic primary afferent neurons.
PLoS One.
8:e60365
PMID: 23565235 -
Ryan et al.
(2013)
Relaxin-3/RXFP3 system regulates alcohol-seeking.
Proc Natl Acad Sci U S A.
110:20789
PMID: 24297931 -
Gozzi et al.
(2013)
Differential effect of orexin-1 and CRF-1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor Yohimbine.
Neuropsychopharmacology.
38:2120
PMID: 23736277 -
Kim et al.
(2011)
Icilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation.
Brain Res.
1384:110
PMID: 21315691 -
Barnea et al.
(2008)
The genetic design of signaling cascades to record receptor activation.
Proc Natl Acad Sci U S A.
105:64
PMID: 18165312 -
Maupoil et al.
(2007)
Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of alpha1- and beta1-adrenoceptors.
Br J Pharmacol.
150:899
PMID: 17325650 -
André et al.
(2006)
Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen.
Protein Sci.
15:1115
PMID: 16597836 -
Marchese et al.
(2003)
Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications.
Br J Pharmacol.
140:520
PMID: 12970091
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Customer Reviews for Yohimbine hydrochloride (1)
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Species: RatAssay Type: In VivoTo model chronic stress, rats were injected daily with yohimbine (0.0, 2.5, or 5.0 mg/kg; i.p.) during the first 7 days of extinction from palatable food self-administration. Injections were combined with SCH-23390 (0.0, 5.0, or 10.0 μg/kg; i.p.), a dopamine D1-like receptor antagonist. Rats were then tested for reinstatement of food seeking triggered by acute yohimbine (0.0, 1.0, or 2.0 mg/kg; i.p.) and pellet priming. Rats treated previously with chronic yohimbine displayed increased responding following acute yohimbine and pellet priming relative to non-chronically stressed rats under certain conditions. SCH-23390 combined with repeated yohimbine injections attenuated these effects.
There are no reviews that match your criteria.