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Yohimbine hydrochloride

Adrenergic alpha-2 Receptor Antagonists Small Molecule

Key Product Details

Description: Selective α2 antagonist
Chemical Name: 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride
Purity: ≥98% (HPLC)
Molecular Weight: 390.91

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Citations for Yohimbine hydrochloride (21)

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  • Chronic yohimbine stress increases vulnerability to reinstatement of palatable food seeking
    Name: Kevin Ball
    Species: Rat
    Assay Type: In Vivo
    To model chronic stress, rats were injected daily with yohimbine (0.0, 2.5, or 5.0 mg/kg; i.p.) during the first 7 days of extinction from palatable food self-administration. Injections were combined with SCH-23390 (0.0, 5.0, or 10.0 μg/kg; i.p.), a dopamine D1-like receptor antagonist. Rats were then tested for reinstatement of food seeking triggered by acute yohimbine (0.0, 1.0, or 2.0 mg/kg; i.p.) and pellet priming. Rats treated previously with chronic yohimbine displayed increased responding following acute yohimbine and pellet priming relative to non-chronically stressed rats under certain conditions. SCH-23390 combined with repeated yohimbine injections attenuated these effects.
    Yohimbine hydrochloride Serum 1127

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