Crotonic Acid

Name: Crotonic Acid
Brand: Tocris Bioscience
SKU: 6660

Tocris Bioscience, part of Bio-Techne | Catalog # 6660

COA / SDS

Enhances reprogramming to pluripotency; facilitates telomere maintenance and increases telomere length

Discontinued Product

6660 has been discontinued. View all Additional Stem Cell Dedifferentiation Products products.

Key Product Details

Description:	Enhances reprogramming to pluripotency; facilitates telomere maintenance and increases telomere length
Chemical Name:	(2E)-2-Butenoic acid
Purity:	≥99% (HPLC)
Molecular Weight:	86.09

View Full Technical Details for Crotonic Acid

Technical Data
Citations

Biological Activity for Crotonic Acid

Crotonic Acid is an induces histone modifications in chemically induced pluripotent stem cells (CiPSCs). Activates gene expression, facilitates telomere maintenance and increases telomere length, and enhances reprogramming of MEFs to iPSCs using a small molecule cocktail including valproic acid (Cat. No. 2815), CHIR 99021 (Cat. No. 4423), tranylcypromine (Cat. No. 3852), forskolin (Cat. No. 1099), AM 580 (Cat. No. 0760), EPZ 004777 (Cat. No. 5567), SGC 0946 (Cat. No. 4541) and PD 0325901 (Cat. No. 4192).

Technical Data for Crotonic Acid

M. Wt	86.09
Formula	C₄H₆O₂
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	107-93-7
PubChem ID	637090
InChi Key	LDHQCZJRKDOVOX-NSCUHMNNSA-N
Smiles	C/C=C/C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Crotonic Acid

References are publications that support the biological activity of the product.

Fu Dynamics of telomere rejuvenation during chemical induction to pluripotent stem cells. Stem Cell Reports 2018 PMID: 29861168

Crotonic Acid

Tocris Bioscience, part of Bio-Techne | Catalog # 6660

Key Product Details

Biological Activity for Crotonic Acid

Technical Data for Crotonic Acid

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Crotonic Acid

Product Documents for Crotonic Acid

COA

Certificate of Analysis

SDS

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