Recombinant Mouse GITR Ligand/TNFSF18 (aa 47-173) Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | NS0 |
Accession #: | AAO89011 |
Applications: | Bioactivity |
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Citations for Recombinant Mouse GITR Ligand/TNFSF18 (aa 47-173) Protein (3)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse GITR Ligand/TNFSF18 (aa 47-173) Protein include:
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Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Sekiya et al. (2018), Nr4a Receptors Regulate Development and Death of Labile Treg Precursors to Prevent Generation of Pathogenic Self-Reactive Cells Cell Rep, 24(6):1627-1638.e6.
PMID: 30089271 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012), Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A, 109(25):9971-6.
PMID: 22665806 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKayamuro H et al. (2009), TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant. Biochem. Biophys. Res. Commun., 384(3):296-300.
PMID: 19406102
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FAQs for Recombinant Mouse GITR Ligand/TNFSF18 (aa 47-173) Protein
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This protein datasheet indicates I need to use a cross-linking antibody, Catalog # MAB050, for biological activity. What is this antibody and is it really necessary?
The antibody is directed against a 6x histidine repeat and is recommended for use as a cross-linker of proteins with 6x his-tag. Crosslinking is often used for proteins that require receptor trimerization and can result greater biological activity. R&D Systems Quality Control tests the performance of these proteins in the presence of the cross-linking antibody. Therefore, it is necessary to use this antibody when trying to achieve the same level of specific activity described in the datasheet.