(-)-Bicuculline methochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0131

GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
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Key Product Details

Description

GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)

View all GABA-A Receptor Antagonists »

Product Description

(-)-Bicuculline methochloride is a methochloride salt of (+)-bicuculline. Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

Methoiodide Salt and Methobromide Salt also available.

Product Specifications

Molecular Weight

417.85

Formula

C21H20ClNO6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

[R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride

CAS Number

38641-83-7

PubChem ID

10047593

InChI Key

RLJKFAMYSYWMND-GRTNUQQKSA-M

SMILES

[H][C@](C(C=CC6=C5OCO6)=C5C(O4)=O)4[C@]2([H])C1=CC3=C(OCO3)C=C1CC[N+](C)2C.[Cl-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 41.78 100

Preparing Stock Solutions for (-)-Bicuculline methochloride

The following data is based on the product molecular weight 417.85

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.39 mL 11.97 mL 23.93 mL
5 mM 0.48 mL 2.39 mL 4.79 mL
10 mM 0.24 mL 1.20 mL 2.39 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (-)-Bicuculline methochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (-)-Bicuculline methochloride

For research use only

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