Human IL-6R alpha Biotinylated Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human |
Immunogen: |
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-6R alpha Leu20-Asp358 Accession # P08887 |
Applications: | ELISA Detection, Western Blot |
Label: | Biotin |
Source: | Polyclonal Goat IgG |
Specificity: |
Detects human IL-6R alpha in ELISAs and Western blots. In sandwich immunoassays, less than 0.1% cross-reactivity with recombinant human (rh) IL‑6, recombinant mouse IL-6, recombinant porcine IL-6, and rhgp130 is observed. |
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Citations for Human IL-6R alpha Biotinylated Antibody (8)
Citations are publications that use Bio-Techne products. Selected citations for Human IL-6R alpha Biotinylated Antibody include:
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CM Flynn et al. (2021), Interleukin-6 controls recycling and degradation, but not internalization of its receptors The Journal of Biological Chemistry, 0(0):100434.
PMID: 33610555 -
Species: Mouse
Sample Types: Plasma
Applications: ELISA CaptureF Mimoto et al. (2020), Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment Cell Reports, 33(12):108542.
PMID: 33357423 -
Species: Human
Sample Types: Protein
Applications: ELISA DevelopmentIwayanagi Y et al. (2015), Inhibitory FcgammaRIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering. J Immunol, 195(7):3198-205.
PMID: 26320252 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development (Detection)Dusterhoft S et al. (2014), A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor. J Biol Chem, 289(23):16336-48.
PMID: 24790088 -
Species: Canine
Sample Types: Whole Tissue
Applications: IHC-FrWood MW et al. (2011), Autocrine effects of interleukin-6 mediate acute-phase proinflammatory and tissue-reparative transcriptional responses of canine bladder mucosa. Infect. Immun., 79(2):708-15.
PMID: 21115724 -
Species: Human
Sample Types: Plasma
Applications: ELISA DevelopmentMozaffarian D et al. (2004), trans fatty acids and systemic inflammation in heart failure. Am. J. Clin. Nutr., 80(6):1521-5.
PMID: 15585763 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA DevelopmentHurst SM et al. (2002), Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J. Immunol., 169(9):5244-51.
PMID: 12391243 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA DevelopmentHurst SM et al. (2001), Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity, 14(6):705-14.
PMID: 11420041
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Customer Reviews for Human IL-6R alpha Biotinylated Antibody (1)
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Application: ELISASample Tested: EDTA PlasmaSpecies: HumanVerified Customer | Posted 06/01/2018Human IL-6 receptor alpha was measured in human plasma samples using an immunoassay comprising of this antibody and MAB227. This antibody was used as the detection and the MAB227 was used as the solid phase capture molecule.
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