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Human IL-10 R alpha Antibody

R&D Systems, Inc. a Bio-Techne Brand

IL‑10 Ra antibody in Human PBMCs by Immunocytochemistry (ICC).
IL‑10 Inhibition of IL‑1 beta  secretion and Neutralization by Human IL‑10 R alpha  Antibody.
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Key Product Details

Species Reactivity: Human
Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑10 R alpha
Accession # Q13651
Applications: Block/Neutralize, Immunocytochemistry/Immunofluorescence, Western Blot
Label: Unconjugated
Source: Polyclonal Goat IgG

Detects human IL‑10 R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant mouse
IL-10 R alpha is observed and less than 5% cross-reactivity with recombinant human (rh) CNTF sR alpha and rhIL-2 sR gamma is observed.

Citations for Human IL-10 R alpha Antibody (1)

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FAQs for Human IL-10 R alpha Antibody

  • Immunoprecipitaiton with the Human IL-10 Rα antibody (Catalog # AF-274-NA) followed by western blotting for Human IL-10 Rα produces a 150 kDa band. What is the identity of this band?

    Human IL-10 Rα antibody has not been validated for immunoprecipitaiton application. The MW of Human IL-10 Rα is about 90-110 kDa and the receptor binds with high affinity to the IL-10 homodimer, which has a MW of 40 kDa. Under non-denaturing conditions, the IL-10Rα may be complexed with IL-10 homodimer to give a 150 kDa band.

Product Documents for Human IL-10 R alpha Antibody

Certificate of Analysis

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