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Voltage-gated Sodium Channel Inhibitors: Small Molecules and Peptides

Voltage-gated sodium channels (NaV) are accountable for potentially initiating and propagating excitable cells, including nerve, muscle, and neuroendocrine cell types. These can also be expressed at low levels in non-excitable cells, but their physiological role is unclear.

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4 results for "Voltage-gated Sodium Channel Inhibitors Small Molecules and Peptides" in Products

4 results for "Voltage-gated Sodium Channel Inhibitors Small Molecules and Peptides" in Products

Voltage-gated Sodium Channel Inhibitors: Small Molecules and Peptides

Voltage-gated sodium channels (NaV) are accountable for potentially initiating and propagating excitable cells, including nerve, muscle, and neuroendocrine cell types. These can also be expressed at low levels in non-excitable cells, but their physiological role is unclear.

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Potent and selective state-independent inhibitor of NaV1.8 sodium channels

Chemical Name: (R)-2-(4-Fluoro-2-methylphenoxy)-N-(3-(S-methylsulfonimidoyl)phenyl)-5-(trifluoromethyl)nicotinamide
Purity: ≥98% (HPLC)
Potent and selective state-independent inhibitor of NaV1.8 sodium channels

Inhibitor of neuronal NaV channels; anticonvulsant

Alternate Names: CBZ
Chemical Name: 5H-Dibenz[b,f]azepine-5-carboxamide
Purity: ≥98% (HPLC)
Inhibitor of neuronal NaV channels; anticonvulsant

Anticonvulsant; inhibits Na+ channel activity

Chemical Name: 10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide
Purity: ≥98% (HPLC)
Anticonvulsant; inhibits Na+ channel activity

Active metabolite of oxcarbazepine (Cat. No. 3864)

Alternate Names: GP 47779
Chemical Name: 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide
Purity: ≥98% (HPLC)
Active metabolite of oxcarbazepine (Cat. No. 3864)
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