V1a Vasopressin R/AVPR1A: Small Molecules and Peptides
AVPR1A acts as a receptor for arginine vasopressin and belongs to the subfamily of G protein-coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. AVPR1A mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. AVPR1A may be involved in social behaviors, including affiliation and attachment.
8 results for "V1a Vasopressin R/AVPR1A Small Molecules and Peptides" in Products
8 results for "V1a Vasopressin R/AVPR1A Small Molecules and Peptides" in Products
V1a Vasopressin R/AVPR1A: Small Molecules and Peptides
AVPR1A acts as a receptor for arginine vasopressin and belongs to the subfamily of G protein-coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. AVPR1A mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. AVPR1A may be involved in social behaviors, including affiliation and attachment.
Antidiuretic hormone
| Alternate Names: | AVP |
| Purity: | ≥95% (HPLC) |
Selective vasopressin V1A antagonist
| Purity: | ≥95% (HPLC) |
Selective, orally active vasopressin V1A receptor antagonist
| Alternate Names: | Relcovaptan |
| Chemical Name: | (2S)-1-[[(2R,3S)-5-Chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-2-pyrrolidinecarboxamide |
| Purity: | ≥98% (HPLC) |
Very high affinity vasopressin V1A and V2 antagonist; orally bioavailable
| Chemical Name: | N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][benzazepin-6(1H)-yl)carbonyl]phenyl-[1,1'-biphenyl]-2-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent non-peptide oxytocin receptor partial agonist; also V1a receptor antagonist
| Chemical Name: | (2S)-N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-2-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)thioxomethyl]-1-pyrrolidinecarboxamide |
| Purity: | ≥97% (HPLC) |
Orally active vasopressin V1 antagonist
| Chemical Name: | N-[3-[4-[[4-(3,4-Dihydro-2-oxo-1(2H)quinolinyl)-1-piperidinyl]carbonyl]phenoxy]propyl]-acetamide |
| Purity: | ≥98% (HPLC) |
Potent and selective vasopressin V2 receptor antagonist; renoprotective and orally active
| Alternate Names: | OPC-41061 |
| Chemical Name: | N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide |
| Purity: | ≥98% (HPLC) |
Potent oxytocin receptor antagonist
| Purity: | ≥98% (HPLC) |
