8 results for "TRPM Blockers Small Molecules and Peptides" in Products
TRPM Blockers: Small Molecules and Peptides
The melastatin-related receptor family (TRPM) is the largest subfamily of the transient receptor potential (TRP) superfamily of ion channels. It contains 8 known members, subdivided into 4 groups, which perform a range of functions including detection of taste and osmolarity, and control of cell proliferation.
Members of the TRPM subfamily are grouped on the basis of sequence homology. The first subgroup includes TRPM1 and TRPM3; the second, TRPM6 and TRPM7; the third, TRPM2 and TRPM8; and the ...
NMDA potentiator; also GABAA inhibitor and TRPM3 activator
| Chemical Name: | (3β)-3-(Sulfooxy)-pregn-5-en-20-one sodium salt |
TRPM8 blocker
| Chemical Name: | N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride |
| Purity: | ≥98% (HPLC) |
TRPM3 blocker
| Chemical Name: | 1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone |
| Purity: | ≥98% (HPLC) |
TRPM8 blocker
| Chemical Name: | N-(4-Fluorophenyl)-3,4-dihydro-1-[4-(trifluoromethyl)phenyl]-2(1H)-isoquinolinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective TRPM8 channel blocker
| Chemical Name: | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective TRPM4 blocker
| Chemical Name: | 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective TRPM8 antagonist; active in vivo
| Chemical Name: | 6-[[[(S)-(3-Fluoro-2-pyridinyl)[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]-3-pyridinecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent TRPM8 antagonist
| Chemical Name: | 3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene |
| Purity: | ≥98% (HPLC) |
