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TrkC Products

Members of the Tyrosine Kinase Receptor (Trk) family (TrkA, TrkB, and TrkC) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth. TrkC is predominantly expressed in the central nervous system.

25 results for "TrkC" in Products

TrkC Products

Members of the Tyrosine Kinase Receptor (Trk) family (TrkA, TrkB, and TrkC) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth. TrkC is predominantly expressed in the central nervous system.

25 results for "TrkC" in Products

WB, Simple Western, IHC, Block
WB, Simple Western, Flow, IHC, Block, CyTOF-ready
BA
WB, IHC
WB, Flow, CyTOF-ready
WB
Catalog #: BAF373
WB
Flow
Catalog #: FAB3731G
Flow
Catalog #: RDC0555
BA

His-tag

Catalog #: FAB3731T
Flow
Catalog #: FAB3731S
Flow
Catalog #: FAB3731N
Flow
Catalog #: FAB3731U
Flow
Catalog #: FAB3731V
Flow

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies

TrkB and TrkC agonist; brain penetrant

Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Potent and selective pan-Trk inhibitor; peripherally restricted

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