
TREM2 Products
TREM2 (Triggering Receptor Expressed on Myeloid cells 2) is a transmembrane protein that is expressed on newly differentiated and alternatively activated tissue macrophages, immature myeloid dendritic cells, and osteoclasts. TREM2 interacts with and modifies signaling through dendritic cell and osteoclast Plexin A1, a semaphorin receptor. It is active in several settings that involve membrane fusion, including phagocytosis of microbes by macrophages and apoptotic neurons by microglia, and formation of osteoclasts and multinucleated giant cells from macrophages. TREM2 signals through the adaptor protein DAP12 and can associate with the linker protein LAT2 to inhibit macrophage activaation. A soluble isoform of TREM2 antagonizes full-length TREM2 and is elevated in cerebrospinal fluid of patients with active multiple sclerosis.
41 results for "TREM2" in Products
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TREM2 Products
TREM2 (Triggering Receptor Expressed on Myeloid cells 2) is a transmembrane protein that is expressed on newly differentiated and alternatively activated tissue macrophages, immature myeloid dendritic cells, and osteoclasts. TREM2 interacts with and modifies signaling through dendritic cell and osteoclast Plexin A1, a semaphorin receptor. It is active in several settings that involve membrane fusion, including phagocytosis of microbes by macrophages and apoptotic neurons by microglia, and formation of osteoclasts and multinucleated giant cells from macrophages. TREM2 signals through the adaptor protein DAP12 and can associate with the linker protein LAT2 to inhibit macrophage activaation. A soluble isoform of TREM2 antagonizes full-length TREM2 and is elevated in cerebrospinal fluid of patients with active multiple sclerosis.
41 results for "TREM2" in Products
Clonality : | Polyclonal |
Host : | Sheep IgG |
Applications : | ELISA, Immunocytochemistry/Immunofluorescence, Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | CyTOF-ready, ELISA, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Knockout Validated |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Simple Plex Cartridge Kit containing TREM2 for use with Human CCS/Plasma/Serum/CSF. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237916 |
Applications : | Western Blot |
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
Assay Range : | 46.9 - 3,000 pg/mL |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #263614 |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Sheep IgG |
Applications : | ELISA, Immunocytochemistry/Immunofluorescence, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #263602 |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Source : | NS0 |
Accession # : | Q9NZC2 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | Q99NH8 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Source : | HEK293 |
Accession # : | XP_005553122.1 |
Applications : | Bioactivity |
Biotinylated
Source : | CHO |
Accession # : | NP_061838.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #237920 |
Applications : | Flow Cytometry |
Source : | NS0 |
Accession # : | NP_061838.1 |
Applications : | Bioactivity |