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749 results for "TIM-3" in Products

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TIM-3 Products

TIM-3 (T cell immunoglobulin and mucin domain-3), also known as HAVCR2 is an immunosuppressive protein that enhances tolerance and inhibits anti-tumor immunity. It is upregulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). TIM-3 ligation by Galectin-9 attenuates CD8+ and Th1 cell responses and promotes the activity of Treg and myeloid derived suppressor cells. Dendritic cell-expressed TIM-3 dampens inflammation by enabling the phagocytosis of apoptotic cells and the cross-presentation of apoptotic cell antigens. TIM-3 also binds the alarmin HMGB1, thereby preventing the activation of TLRs in response to released tumor cell DNA.

Recombinant Cynomolgus Monkey TIM-3 Fc Chimera Protein, CF

Catalog #: 7914-TM
(1)
Citations (2)
Product Documents
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
EHH54703
Applications:
Binding Activity, Bioactivity
Recombinant Cynomolgus Monkey TIM-3 Fc Chimera Protein Bioactivity

Human TIM-3 Antibody

Catalog #: AF2365
(3)
Citations (53)
Product Documents
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
KO, IHC, WB, Flow, Dual ISH-IHC, + 1 More
TIM-3 antibody in Human Tonsil Using Dual RNAscope®ISH and IHC.
(5)

Human TIM-3 Quantikine ELISA Kit

Catalog #: DTIM30
Citations (10)
Product Documents
Reactivity:
Human
Assay Range:
31.3-2000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine)
Applications:
ELISA
Human TIM-3 ELISA Standard Curve
(2)

Human TIM-3 Antibody (344823) [PE] Best Seller

Catalog #: FAB2365P
(1)
Citations (61)
Product Documents

Clone 344823 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Rat IgG2A Monoclonal Clone #344823
Applications:
Flow
Detection of TIM-3 antibody in Human Blood Monocytes antibody by Flow Cytometry.
(4)

Simple Plex Human TIM-3 Cartridge

Catalog #: SPCKB-PS-001049
Product Documents

Simple Plex Human TIM-3 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated with PS (Plasma/Serum).

Reactivity:
Human
Applications:
Simple Plex
Ella Automated ELISA Platform and Simple Plex Human TIM-3 Assay
(3)

Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.

Build My Cartridge

Rat IL-2 Quantikine ELISA Kit

Catalog #: R2000
Citations (34)
Product Documents
Reactivity:
Rat
Assay Range:
31.2-2000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Rat IL-2 ELISA Standard Curve
(2)

Human TIM-3 Antibody (344823)

Catalog #: MAB2365
Citations (23)
Product Documents

Clone 344823 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Rat IgG2A Monoclonal Clone #344823
Applications:
Flow, CyTOF-ready
Detection of TIM‑3 antibody in Human Monocytes antibody by Flow Cytometry.

Recombinant Human TIM-3 Fc Chimera Protein, CF

Catalog #: 2365-TM
(4)
Citations (27)
Product Documents
Reactivity:
Human
Source:
NS0
Accession #:
Q8TDQ0
Applications:
Binding Activity
R&D Systems Recombinant Proteins and Enzymes

Human TIM-3 Antibody (344823) [APC]

Catalog #: FAB2365A
(3)
Citations (25)
Product Documents

Clone 344823 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Rat IgG2A Monoclonal Clone #344823
Applications:
Flow
Detection of TIM‑3 antibody in Human Blood Monocytes antibody by Flow Cytometry.
(2)

Mouse TIM-3 Antibody

Catalog #: AF1529
Citations (5)
Product Documents
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, Flow, CyTOF-ready
Detection of Mouse TIM-3 antibody by Western Blot.
(6)

Human TIM-3 Antibody (2321C)

Catalog #: MAB23652
Citations (7)
Product Documents

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2321C
Applications:
IHC, WB, Flow, CyTOF-ready
Detection of Human TIM-3 antibody by Western Blot.
(6)

Human TIM-3 Antibody (344801)

Catalog #: MAB23651
Citations (20)
Product Documents
Reactivity:
Human
Details:
Rat IgG1 Monoclonal Clone #344801
Applications:
Func

Human TIM-3 Antibody (344823) [Alexa Fluor® 488]

Catalog #: FAB2365G
Citations (6)
Product Documents

Clone 344823 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Rat IgG2A Monoclonal Clone #344823
Applications:
Flow
Detection of TIM-3 antibody in Human PBMCs Monocytes antibody by Flow Cytometry.
(2)

TIM-3 Antibody (TIM3/3113) - Azide and BSA Free

Catalog #: NBP2-79836
Product Documents
Reactivity:
Human
Details:
Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113
Applications:
IHC, ELISA, Endotoxin
Immunohistochemistry-Paraffin: TIM-3 Antibody (TIM3/3113) - Azide and BSA Free [NBP2-79836]
(7)

Human TIM-3 DuoSet ELISA

Catalog #: DY2365
Citations (10)
Product Documents
Reactivity:
Human
Assay Range:
62.5-4000 pg/mL
Applications:
ELISA
Human TIM-3 ELISA Standard Curve

TIM-3 Antibody (TIM3/3113)

Catalog #: NBP2-79702
Product Documents
Reactivity:
Human
Details:
Mouse IgG2a Kappa Monoclonal Clone #TIM3/3113
Applications:
IHC, ELISA, Endotoxin
Immunohistochemistry-Paraffin: TIM-3 Antibody (TIM3/3113) [NBP2-79702]
(6)

Recombinant Mouse TIM-3 Fc Chimera Protein, CF

Catalog #: 1529-TM
Citations (7)
Product Documents
Reactivity:
Mouse
Source:
NS0
Accession #:
AAL65156
Applications:
Binding Activity
R&D Systems Recombinant Proteins and Enzymes

TIM-3 Antibody (OTI2E2) - Azide and BSA Free

Catalog #: NBP2-74520
Product Documents
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #OTI2E2
Applications:
IHC, WB
Western Blot: TIM-3 Antibody (OTI2E2)Azide and BSA Free [NBP2-74520]
(7)

Mouse TIM-3 Antibody (215015)

Catalog #: MAB15291
Citations (2)
Product Documents
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #215015
Applications:
WB

TIM-3 Antibody (F38-2E2) - BSA Free

Catalog #: NBP2-27220
Product Documents

Clone F38-2E2 was used by HLDA to establish CD designation.

Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #F38-2E2
Applications:
Flow
Flow Cytometry: TIM-3 Antibody (F38-2E2) - BSA Free [NBP2-27220]
(3)

TIM-3 Antibody (F38-2E2) - Azide and BSA Free

Catalog #: NBP2-27221
Product Documents

Clone F38-2E2 was used by HLDA to establish CD designation.

Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #F38-2E2
Applications:
Flow, CyTOF-ready
Flow Cytometry: TIM-3 Antibody (F38-2E2) - Azide Free [NBP2-27221]
(3)

Recombinant Human TIM-3 His-tag Protein, CF

Catalog #: 10241-TI
Citations (1)
Product Documents
Reactivity:
Human
Source:
CHO
Accession #:
AAL65157.1
Applications:
Bioactivity
Recombinant Human TIM-3 His-tag Protein Binding Activity
(2)

Mouse TIM-3 Antibody (215008) [PE]

Catalog #: FAB1529P
(1)
Citations (13)
Product Documents
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #215008
Applications:
Flow
Detection of TIM-3 antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.

TIM-3 Antibody (OTI2E2)

Catalog #: NBP2-45933
Product Documents
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #OTI2E2
Applications:
IHC, WB
Immunohistochemistry: TIM-3 Antibody (OTI2E2) [NBP2-45933]
(6)

TIM-3 Antibody (OTI2E2)

Catalog #: NBP2-45933
Product Documents
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #OTI2E2
Applications:
IHC, WB
Immunohistochemistry: TIM-3 Antibody (OTI2E2) [NBP2-45933]
(6)
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