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Thrombomodulin/BDCA-3 Products
Thrombomodulin (TM), also known as CD141 and BDCA3, is a transmembrane expressed on vascular endothelial cells (EC), arterial smooth muscle cells, monocytes, and macrophages. It binds Thrombin and enhances the Thrombin-mediated activation of the anti-coagulant Protein C and the anti-fibrinolytic TAFI/Carboxypeptidase B2. Thrombomodulin also inhibits the ability of Thrombin to activate several pro-coagulant proteins (e.g. Fibrinogen, Factor V, Factor XIII, PAR-1). Thrombomodulin exerts multiple anti-inflammatory effects and reduces the severity of disease involving chronic inflammation. In cancer, Thrombomodulin suppresses tumor angiogenesis, growth, and epithelial-mesenchymal transition. Soluble fragments of Thrombomodulin are elevated in the serum, urine, and synovial fluid during coagulation disorders, inflammation, and organ failure.
34 results for "Thrombomodulin/BDCA-3" in Products
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Thrombomodulin/BDCA-3 Products
Thrombomodulin (TM), also known as CD141 and BDCA3, is a transmembrane expressed on vascular endothelial cells (EC), arterial smooth muscle cells, monocytes, and macrophages. It binds Thrombin and enhances the Thrombin-mediated activation of the anti-coagulant Protein C and the anti-fibrinolytic TAFI/Carboxypeptidase B2. Thrombomodulin also inhibits the ability of Thrombin to activate several pro-coagulant proteins (e.g. Fibrinogen, Factor V, Factor XIII, PAR-1). Thrombomodulin exerts multiple anti-inflammatory effects and reduces the severity of disease involving chronic inflammation. In cancer, Thrombomodulin suppresses tumor angiogenesis, growth, and epithelial-mesenchymal transition. Soluble fragments of Thrombomodulin are elevated in the serum, urine, and synovial fluid during coagulation disorders, inflammation, and organ failure.
34 results for "Thrombomodulin/BDCA-3" in Products
| Sensitivity : | 19.1 pg/mL |
| Assay Range : | 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
| Sensitivity : | 27 pg/mL |
| Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #461714 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Source : | NS0 |
| Accession # : | P07204 |
| Applications : | Enzyme Activity |
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #501733 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Source : | NS0 |
| Accession # : | P15306 |
| Applications : | Enzyme Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #501727 |
| Applications : | ELISA Detection |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #501733 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #461714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #501727 |
| Applications : | Immunoprecipitation, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #461714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #501733 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #501733 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #501733 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #461714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #461714 |
| Applications : | Flow Cytometry |
| Assay Range : | 93.8 - 6,000 pg/mL |
| Applications : | ELISA |
For use with catalog number DTHBD0
| Applications : | Control, ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #501733 |
| Applications : | Flow Cytometry |
