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Spike S1 Subunit: Proteins and Enzymes

Spike S1 subunit refers to the N-terminal part of the coronavirus Spike protein. The S1 subunit contains an N-terminal domain in addition to the much-studied receptor binding domain (RBD). Spatially, the S1 subunit represents the most membrane-distal portion of the spike protein. For SARS-CoV-2, this subunit, specifically the RBD domain, is responsible for binding to ACE-2 on the surface of human cells and initiating viral entry. Because this interaction is so important for viral entry into host cells, the RBD domain has been the focus of therapeutic and vaccine development for COVID-19. The N-terminal domain of the S1 subunit may also be involved in receptor binding independent of ACE-2. Current research is underway to better understand this domain as it may unlock new therapeutic strategies to fight SARS-CoV-2.

41 results for "Spike S1 Subunit Proteins and Enzymes" in Products

Spike S1 Subunit: Proteins and Enzymes

Spike S1 subunit refers to the N-terminal part of the coronavirus Spike protein. The S1 subunit contains an N-terminal domain in addition to the much-studied receptor binding domain (RBD). Spatially, the S1 subunit represents the most membrane-distal portion of the spike protein. For SARS-CoV-2, this subunit, specifically the RBD domain, is responsible for binding to ACE-2 on the surface of human cells and initiating viral entry. Because this interaction is so important for viral entry into host cells, the RBD domain has been the focus of therapeutic and vaccine development for COVID-19. The N-terminal domain of the S1 subunit may also be involved in receptor binding independent of ACE-2. Current research is underway to better understand this domain as it may unlock new therapeutic strategies to fight SARS-CoV-2.

41 results for "Spike S1 Subunit Proteins and Enzymes" in Products

BA

Sf21 Insect Cell Expressed

HEK293 Expressed

BA

Omnicron Variant

BA

Delta Covid Variant

BA

Omicron Variant

Sf21 Insect Cell Expressed

BA

Omnicron Variant

BA
BA

Tn5 Insect Cell Expressed

BA

CHO Expressed

BA

Biotinylated

His-tag. Biotinylated via Amines

BA

D614G, Q677P, 20C-US Regional Variant

BA
BA
BA
BA
BA
BA

S477N, D614G

BA

HEK293 Expressed

BA

CHO Expressed

BA
BA

CHO Expressed

BA

A222V, D614G

CHO Expressed

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