
Spike S1 Subunit Products
Spike S1 subunit refers to the N-terminal part of the coronavirus Spike protein. The S1 subunit contains an N-terminal domain in addition to the much-studied receptor binding domain (RBD). Spatially, the S1 subunit represents the most membrane-distal portion of the spike protein. For SARS-CoV-2, this subunit, specifically the RBD domain, is responsible for binding to ACE-2 on the surface of human cells and initiating viral entry. Because this interaction is so important for viral entry into host cells, the RBD domain has been the focus of therapeutic and vaccine development for COVID-19. The N-terminal domain of the S1 subunit may also be involved in receptor binding independent of ACE-2. Current research is underway to better understand this domain as it may unlock new therapeutic strategies to fight SARS-CoV-2.
67 results for "Spike S1 Subunit" in Products
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
Spike S1 Subunit Products
Spike S1 subunit refers to the N-terminal part of the coronavirus Spike protein. The S1 subunit contains an N-terminal domain in addition to the much-studied receptor binding domain (RBD). Spatially, the S1 subunit represents the most membrane-distal portion of the spike protein. For SARS-CoV-2, this subunit, specifically the RBD domain, is responsible for binding to ACE-2 on the surface of human cells and initiating viral entry. Because this interaction is so important for viral entry into host cells, the RBD domain has been the focus of therapeutic and vaccine development for COVID-19. The N-terminal domain of the S1 subunit may also be involved in receptor binding independent of ACE-2. Current research is underway to better understand this domain as it may unlock new therapeutic strategies to fight SARS-CoV-2.
67 results for "Spike S1 Subunit" in Products
Sf21 Insect Cell Expressed
Source : | Sf 21 (baculovirus) |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035753 |
Applications : | Block/Neutralize, ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035206 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035206 |
Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2811A |
Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
HEK293 Expressed
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035226 |
Applications : | CyTOF-ready, Flow Cytometry |
RUO Quantitative ELISA. Patent Pending.
Sensitivity : | 3.2 AU/mL |
Assay Range : | 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Omnicron Variant
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035740 |
Applications : | Block/Neutralize, ELISA |
Available in the EU and UK only. For research testing.
Sensitivity : | 3.2 AU/mL |
Assay Range : | 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035226 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035226 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035341 |
Applications : | Western Blot |
Delta Covid Variant
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035206 |
Applications : | Flow Cytometry |
Omicron Variant
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Sf21 Insect Cell Expressed
Source : | Sf 21 (baculovirus) |
Accession # : | NP_828851.1 |
Applications : | Bioactivity |
Omnicron Variant
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | AAP41037.1 |
Applications : | Bioactivity |
Tn5 Insect Cell Expressed
Source : | T. ni (baculovirus) |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
CHO Expressed
Source : | CHO |
Accession # : | YP_009825051.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035206 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035224 |
Applications : | Block/Neutralize |
Biotinylated
Source : | CHO |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |