550 results for "SIRP alpha/CD172a" in Products
SIRP alpha/CD172a Products
Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1), BIT (Brain Ig-like molecule with Tyrosine-based activation motifs) and previously, MyD-1 (Myeloid/Dendritic-1), is a transmembrane glycoprotein belonging to the SIRP/SHPS (CD172) family within the immunoglobulin superfamily. SIRP alpha contains cytoplasmic ITIM domains and produces negative regulatory signals. Through adhesion to CD47/IAP (integrin-associated protein), SIRP alpha inhibits clearance of CD47high young erythrocytes and platelets and promotes macrophage fusion during osteoclastogenesis. SIRP alpha recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Applications: | WB, Flow, CyTOF-ready, ICC |
| Source: | CHO |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602407 |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Source: | CHO |
| Accession #: | NP_542970.1 |
| Applications: | BA |
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #772734 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Applications: | Flow |
| Reactivity: | Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602407 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602407 |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #772734 |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602404 |
| Reactivity: | Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602404 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #772734 |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |