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SIRP alpha/CD172a Products

Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1), BIT (Brain Ig-like molecule with Tyrosine-based activation motifs) and previously, MyD-1 (Myeloid/Dendritic-1), is a transmembrane glycoprotein belonging to the SIRP/SHPS (CD172) family within the immunoglobulin superfamily. SIRP alpha contains cytoplasmic ITIM domains and produces negative regulatory signals. Through adhesion to CD47/IAP (integrin-associated protein), SIRP alpha inhibits clearance of CD47high young erythrocytes and platelets and promotes macrophage fusion during osteoclastogenesis. SIRP alpha recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.

38 results for "SIRP alpha/CD172a" in Products

SIRP alpha/CD172a Products

Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1), BIT (Brain Ig-like molecule with Tyrosine-based activation motifs) and previously, MyD-1 (Myeloid/Dendritic-1), is a transmembrane glycoprotein belonging to the SIRP/SHPS (CD172) family within the immunoglobulin superfamily. SIRP alpha contains cytoplasmic ITIM domains and produces negative regulatory signals. Through adhesion to CD47/IAP (integrin-associated protein), SIRP alpha inhibits clearance of CD47high young erythrocytes and platelets and promotes macrophage fusion during osteoclastogenesis. SIRP alpha recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.

38 results for "SIRP alpha/CD172a" in Products

WB, Flow, CyTOF-ready, ICC

Potent glutaminyl cyclase inhibitor; disrupts binding of SIRP-α to CD47

Catalog #: FAB7307V
Flow
Flow
Catalog #: FAB7307N
Flow
ELISA
Flow
Catalog #: RDC1913
BA

Biotinylated

BA

Biotinylated

BA

Biotinylated via amines

WB, Simple Western
WB, Simple Western
BA
BA
Catalog #: FAB4546N
Flow
Catalog #: FAB4546G
Flow
ELISA
WB, Flow, CyTOF-ready, Neut
Catalog #: FAB4546R
Flow
Catalog #: FAB7307R
Flow
Catalog #: FAB7307S
Flow
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