RBP4/Retinol-Binding Protein 4 Products
Retinol-binding protein 4 (RBP4) is a Lipocalin superfamily molecule that transports vitamin A (retinol) and retinaldehyde in the serum. Retinaldehyde is the critical chromophore in the rhodopsin photoreceptor, while both it and retinoic acid regulate a multitude of cellular differentiation and proliferation effects through the intracellular receptors RAR and RXR. RBP4 is secreted primarily by hepatocytes and adipocytes into the blood where the RBP4-retinol complex interacts with transthyretin (TTR). Formation of the complex with TTR increases the serum half-life of RBP4 by preventing RBP4 filtration through the kidney. The C-terminally processed forms of RBP4, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. RBP4 promotes hyperglycemia, and its upregulation in visceral and liver adipocytes leads to elevated serum levels.
368 results for "RBP4/Retinol-Binding Protein 4" in Products
368 results for "RBP4/Retinol-Binding Protein 4" in Products
RBP4/Retinol-Binding Protein 4 Products
Retinol-binding protein 4 (RBP4) is a Lipocalin superfamily molecule that transports vitamin A (retinol) and retinaldehyde in the serum. Retinaldehyde is the critical chromophore in the rhodopsin photoreceptor, while both it and retinoic acid regulate a multitude of cellular differentiation and proliferation effects through the intracellular receptors RAR and RXR. RBP4 is secreted primarily by hepatocytes and adipocytes into the blood where the RBP4-retinol complex interacts with transthyretin (TTR). Formation of the complex with TTR increases the serum half-life of RBP4 by preventing RBP4 filtration through the kidney. The C-terminally processed forms of RBP4, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. RBP4 promotes hyperglycemia, and its upregulation in visceral and liver adipocytes leads to elevated serum levels.
| Applications: | PAGE |
| Applications: | WB |
![Western Blot: RBP4/Retinol-Binding Protein 4 Overexpression Lysate [NBL1-15228]](https://resources.bio-techne.com/images/products/RBP4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-15228-img0002.jpg "Western Blot: RBP4/Retinol-Binding Protein 4 Overexpression Lysate [NBL1-15228]")
| Source: | NS0 |
| Accession #: | Q00724 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | P02753 |
| Applications: | Bind |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |
![RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) - Azide and BSA Free Protein Array: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) - Azide and BSA Free [NBP3-24345] -](https://resources.bio-techne.com/images/products/nbp3-24345_ms-rbp4-mab-rbp4-4046-azide-bsa-free-2412025801639.jpg "Protein Array: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) - Azide and BSA Free [NBP3-24345] -")
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |
![RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) Protein Array: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) [NBP3-23835] -](https://resources.bio-techne.com/images/products/nbp3-23835_mouse-rbp4-retinol-binding-protein-4-mab-rbp4-4046-2412025872391.jpg "Protein Array: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) [NBP3-23835] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rRBP4/7372 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
![RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) Immunohistochemistry-Paraffin: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [NBP3-23836] -](https://resources.bio-techne.com/images/products/nbp3-23836_rabbit-rbp4-retinol-binding-protein-4-mab-rbp4-8090r-2412025872360.jpg "Immunohistochemistry-Paraffin: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [NBP3-23836] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
![RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) - Azide and BSA Free Immunohistochemistry-Paraffin: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) - Azide and BSA Free [NBP3-24346] -](https://resources.bio-techne.com/images/products/nbp3-24346_rb-rbp4-mab-rbp4-8090r-azide-bsa-free-24120257592889.jpg "Immunohistochemistry-Paraffin: RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) - Azide and BSA Free [NBP3-24346] -")
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
![RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-24346cl1_rabbit-rbp4-retinol-binding-protein-4-mab-rbp4-8090r-cl1-299202515262113.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rRBP4/7372 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Janelia Fluor® 525]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Janelia Fluor® 669]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) [Alexa Fluor™ Plus 647]
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Alexa Fluor™ Plus 647]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Alexa Fluor™ Plus 555]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Alexa Fluor™ Plus 680]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Alexa Fluor™ Plus 488]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/8090R) [Alexa Fluor™ Plus 594]
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RBP4/8090R |
| Applications: | IHC |
RBP4/Retinol-Binding Protein 4 Antibody (RBP4/4046) [Alexa Fluor™ Plus 555]
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #RBP4/4046 |
| Applications: | IHC |