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7 results for "Ras GTPase Inhibitors Small Molecules and Peptides" in Products

Ras GTPase Inhibitors Small Molecules and Peptides

Potent farnesyl diphosphate (FPP) synthase inhibitor

Alternate Names:
Zometa
Chemical Name:
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Purity:
≥98%
Potent farnesyl diphosphate (FPP) synthase inhibitor

Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker

Chemical Name:
N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride
Purity:
≥98%
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

Chemical Name:
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
Purity:
≥98%
Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Chemical Name:
[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity:
≥98%
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

Chemical Name:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
Purity:
≥98%
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

Mutation-selective inhibitor of KRASG12C

Alternate Names:
Adagrasib
Chemical Name:
4-[7-(8-Chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-(2S)-2-piperazineacetonitrile
Purity:
≥98%
Mutation-selective inhibitor of KRASG12C

Potent and selective KRASG12C inhibitor

Alternate Names:
Sotorasib
Chemical Name:
(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
Purity:
≥98%
Potent and selective KRASG12C inhibitor
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