PBEF/Visfatin: Small Molecules and Peptides
PBEF, also called Nampt or visfatin, is a ubiquitous 52 kDa nicotinamide phosphoribosyltransferase. PBEF is the rate-limiting component in the biosynthesis of NAD+, and functions in the cytoplasm to regulate energy metabolism during stress responses and immune activation. Although it lacks a signal sequence, PBEF appears to be secreted by visceral adipose and functions as a noncompetitive insulin mimetic. Mouse PBEF shows 96% and > 99% aa identity with human and rat PBEF, respectively.
2 results for "PBEF/Visfatin Small Molecules and Peptides" in Products
2 results for "PBEF/Visfatin Small Molecules and Peptides" in Products
PBEF/Visfatin: Small Molecules and Peptides
PBEF, also called Nampt or visfatin, is a ubiquitous 52 kDa nicotinamide phosphoribosyltransferase. PBEF is the rate-limiting component in the biosynthesis of NAD+, and functions in the cytoplasm to regulate energy metabolism during stress responses and immune activation. Although it lacks a signal sequence, PBEF appears to be secreted by visceral adipose and functions as a noncompetitive insulin mimetic. Mouse PBEF shows 96% and > 99% aa identity with human and rat PBEF, respectively.
NAMPT inhibitor; active in vivo and cytotoxic
| Chemical Name: | N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine |
| Purity: | ≥98% (HPLC) |
NAMPT inhibitor; also GLUT1 inhibitor
| Chemical Name: | 4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide |
| Purity: | ≥98% (HPLC) |
