CHS 828

Tocris Bioscience, part of Bio-Techne | Catalog # 6753

NAMPT inhibitor; active in vivo and cytotoxic
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Key Product Details

Description

NAMPT inhibitor; active in vivo and cytotoxic

View all NAMPT Inhibitors »

Product Description

CHS 828 is a NAMPT inhibitor. Decreases cellular level of NAD+. Selectively increases intracellular ROS levels in cancer cells but not normal cells. Active in vivo and cytotoxic.

Product Specifications

Molecular Weight

371.86

Formula

C19H22ClN5O

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine

CAS Number

200484-11-3

PubChem ID

148198

InChI Key

BOIPLTNGIAPDBY-UHFFFAOYSA-N

SMILES

ClC1=CC=C(C=C1)OCCCCCCN/C(NC#N)=N/C2=CC=NC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.19 100

Preparing Stock Solutions for CHS 828

The following data is based on the product molecular weight 371.86

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.69 mL 13.45 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL
10 mM 0.27 mL 1.34 mL 2.69 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for CHS 828

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CHS 828

For research use only

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