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22 results for "Pappalysin-1/PAPP-A" in Products
Pappalysin-1/PAPP-A Products
Pappalysins comprise one of the five families of Metzincins (other families include ADAMs/ADAMTSs, MMPs, Astacins, and Serralysins). Pappalysin-1 (PAPP-A) is an important pregnancy protein and increases in plasma by a factor of about 150 during pregnancy. Reduced maternal serum PAPP-A is a major marker of Down syndrome in the first trimester of pregnancy. PAPP-A cleaves IGFBP-4 and -5 (insulin-like growth factor-binding protein-4 and 5) at a single site, resulting in the release of bioactive IGF. Pappalysin-2 (PAPP-A2; also called PAPP-E) shares 45% amino acid identity with PAPP-A and cleaves IGFBP-2.
Reactivity:
Human
Source:
NS0
Accession #:
Q13219
Applications:
Enzyme Activity
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC
![Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody [NBP1-90087]](https://resources.rndsystems.com/images/products/Pappalysin-1-PAPP-A-Antibody-Immunohistochemistry-Paraffin-NBP1-90087-img0012.jpg "Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody [NBP1-90087]")
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #PAPP A 1-1
Applications:
IHC, WB, ELISA
![Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody (PAPP A 1-1) - BSA Free [NBP2-21614]](https://resources.rndsystems.com/images/products/Pappalysin-1-PAPP-A-Antibody-PAPP-A-1-1-BSA-Free-Immunohistochemistry-Paraffin-NBP2-21614-img0001.jpg "Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody (PAPP A 1-1) - BSA Free [NBP2-21614]")
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #10E1cc
Applications:
WB, ELISA, IP
![Western Blot: Pappalysin-1/PAPP-A Antibody (10E1cc) [NB120-8346]](https://resources.rndsystems.com/images/products/PAPP-A-Antibody-10E1-Western-Blot-NB120-8346-img0002.jpg "Western Blot: Pappalysin-1/PAPP-A Antibody (10E1cc) [NB120-8346]")
Reactivity:
Mouse
Source:
NS0
Accession #:
Q8R4K8-1
Applications:
Enzyme Activity
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #9
Applications:
IHC, WB, ELISA
![Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody (9) - BSA Free [NBP1-05116]](https://resources.rndsystems.com/images/products/Pappalysin-1-PAPP-A-Antibody-NA-BSA-Free-Immunohistochemistry-Paraffin-NBP1-05116-img0002.jpg "Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody (9) - BSA Free [NBP1-05116]")
Reactivity:
Rat
Assay Range:
0.16 - 10 ng/mL
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #PAPP A1-24
Applications:
IHC, WB, ELISA
![Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody (PAPP A1-24) - BSA Free [NBP1-05043]](https://resources.rndsystems.com/images/products/Pappalysin-1-PAPP-A-Antibody-PAPP-A1-24-BSA-Free-Immunohistochemistry-Paraffin-NBP1-05043-img0001.jpg "Immunohistochemistry-Paraffin: Pappalysin-1/PAPP-A Antibody (PAPP A1-24) - BSA Free [NBP1-05043]")
Reactivity:
Monkey
Assay Range:
0.78 - 50 ng/mL
Applications:
ELISA
Reactivity:
Human, Rat
Details:
Mouse IgG1 kappa Monoclonal Clone #C5
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #7A6
Applications:
ELISA, IP
![Western Blot: Pappalysin-1/PAPP-A Antibody (7A6) [NB100-73060]](https://resources.rndsystems.com/images/products/Pappalysin-1-PAPP-A-Antibody-7A6-Western-Blot-NB100-73060-img0003.jpg "Western Blot: Pappalysin-1/PAPP-A Antibody (7A6) [NB100-73060]")
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #5H9
Applications:
ELISA, IP
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #H4
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #H6
Applications:
IHC
Reactivity:
Human
Details:
Rabbit IgG Kappa Monoclonal Clone #PAPPA/8804R
Applications:
IHC
Reactivity:
Human
Details:
Rabbit IgG Kappa Monoclonal Clone #PAPPA/8804R
Applications:
IHC
Reactivity:
Mouse
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #10E2cc
Applications:
ELISA, IP
Reactivity:
Mouse
Assay Range:
0.156 - 10 ng/mL (example only; lot dependent)
Applications:
ELISA
![Mouse Pappalysin-1/PAPP-A - Ready-To-Use ELISA Kit (Colorimetric) ELISA: Mouse Pappalysin-1/PAPP-A - Ready-To-Use ELISA Kit (Colorimetric) [NBP3-53254]](https://resources.rndsystems.com/images/products/elisa/nbp3-53254_-elisa-639197505237707548.png "ELISA: Mouse Pappalysin-1/PAPP-A - Ready-To-Use ELISA Kit (Colorimetric) [NBP3-53254]")
Reactivity:
Mouse
Assay Range:
0.156 - 10 ng/mL (example only; lot dependent)
Applications:
ELISA
![Mouse Pappalysin-1/PAPP-A ELISA Kit (Colorimetric) ELISA: Mouse Pappalysin-1/PAPP-A ELISA Kit (Colorimetric) [NBP3-56807]](https://resources.rndsystems.com/images/products/elisa/nbp3-56807_-elisa-639197505803771245.png "ELISA: Mouse Pappalysin-1/PAPP-A ELISA Kit (Colorimetric) [NBP3-56807]")
Reactivity:
Human
Source:
E. coli
Applications:
AC