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15 results for "pak-inhibitors&view=expanded" in Products

Quantikine Quickit version available - results in 90 minutes (QK1757).

Reactivity:
Human
Assay Range:
0.156-10 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma, Saliva, Urine)
Applications:
ELISA
Human Lipocalin-2/NGAL ELISA Standard Curve
(2)
Reactivity:
Human
Assay Range:
0.156-10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva)
Applications:
ELISA
Human TIMP-1 ELISA Standard Curve
(2)
Reactivity:
Human
Assay Range:
0.156-10 ng/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine, Human Milk)
Applications:
ELISA
Human MIF ELISA Standard Curve
(2)
Reactivity:
Rat
Assay Range:
37.5-2400 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)
Applications:
ELISA
Rat TIMP-1 ELISA Standard Curve
(2)

Group I PAK inhibitor

Chemical Name:
1,1'-Dithiodi-2-naphthtol
Purity:
≥96%
Group I PAK inhibitor

Potent PAK inhibitor; brain penetrant and orally bioavailable

Chemical Name:
6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
Purity:
≥98%
Potent PAK inhibitor; brain penetrant and orally bioavailable

Negative control of NVS PAK1 1 (Cat. No. 6132)

Chemical Name:
(3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide
Purity:
≥98%
Negative control of NVS PAK1 1 (Cat. No. 6132)

Potent group I PAK inhibitor

Chemical Name:
6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Purity:
≥98%
Potent group I PAK inhibitor

High affinity group I PAK inhibitor

Chemical Name:
8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Purity:
≥98%
High affinity group I PAK inhibitor

Potent and selective PAK1 inhibitor

Chemical Name:
(3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide
Purity:
≥98%
Potent and selective PAK1 inhibitor
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