IPA 3

Tocris Bioscience, part of Bio-Techne | Catalog # 3622

Group I PAK inhibitor
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Key Product Details

Description

Group I PAK inhibitor

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Product Description

IPA 3 is a group I p21-activated kinase (PAK) inhibitor (IC50 = 2.5 μM at PAK1). Targets the autoregulatory mechanism and promotes the inactive conformation of PAKs. Inhibits PAK1-mediated signaling in vivo; potential anti-tumor agent.

Negative Control also available.

Product Specifications

Molecular Weight

350.45

Formula

C20H14O2S2

Storage

Store at -20°C

Purity

≥96% (HPLC)

Chemical Name

1,1'-Dithiodi-2-naphthtol

CAS Number

42521-82-4

PubChem ID

521106

InChI Key

RFAXLXKIAKIUDT-UHFFFAOYSA-N

SMILES

OC2=C(SSC3=C(O)C=CC4=C3C=CC=C4)C1=CC=CC=C1C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.28 75

Preparing Stock Solutions for IPA 3

The following data is based on the product molecular weight 350.45

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 3.80 mL 19.02 mL 38.05 mL
3.75 mM 0.76 mL 3.80 mL 7.61 mL
7.5 mM 0.38 mL 1.90 mL 3.80 mL
37.5 mM 0.08 mL 0.38 mL 0.76 mL

Calculators

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Reconstitution Calculator

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Product Documents for IPA 3

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IPA 3

For research use only

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