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Other ER Stress/UPR Inhibitors: Small Molecules and Peptides

Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.

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9 results for "Other ER Stress/UPR Inhibitors Small Molecules and Peptides" in Products

Other ER Stress/UPR Inhibitors: Small Molecules and Peptides

Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.

Show More

9 results for "Other ER Stress/UPR Inhibitors Small Molecules and Peptides" in Products

Selective inhibitor of eIF2α dephosphorylation

Selective and reversible p97 ATPase inhibitor

p97 ATPase (VCP) inhibitor

Potent inhibitor of ER-associated protein degradation and translocation

Potent and selective p97 ATPase (VCP) allosteric inhibitor

Dimeric Smac mimetic; potent IAP inhibitor

ATP-competitive inhibitor of p97 ATPase

SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Potent and selective ASK1 inhibitor; orally bioavailable

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