10 results for "Orphan 7-TM Receptor Agonists Small Molecules and Peptides" in Products
Orphan 7-TM Receptor Agonists: Small Molecules and Peptides
Orphan 7-TM receptors (orphan GPCRs) are receptors for which there are no defined ligands. Traditionally, receptors are characterized by specific ligands and stimuli; the search for ligands of orphan receptors is akin to reverse-engineering this process, since the receptors have been identified but they are responding to as-yet unidentified endogenous ligands. There are approximately 150 orphan 7-TM receptors, subdivided into three classes: Class A, Class B and Class C. Orphan G-protein coupled ...
Potent GPR37 and GPR37L1 agonist
| Purity: | ≥95% (HPLC) |
Potent and selective GPR39 agonist
| Chemical Name: | N-[3-Chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective GPR52 agonist; orally bioavailable and BBB permeable
| Alternate Names: | TP-024 |
| Chemical Name: | 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective GPR139 agonist
| Chemical Name: | 3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide |
| Purity: | ≥98% (HPLC) |
Selective positive allosteric modulator at GPR68
| Chemical Name: | 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol |
| Purity: | ≥98% (HPLC) |
GPR35 agonist
| Chemical Name: | 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile |
| Purity: | ≥98% (HPLC) |
GPR27 agonist
| Chemical Name: | 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide |
| Purity: | ≥98% (HPLC) |
Selective HCA1 agonist
| Chemical Name: | 3,5-Dihydroxybenzoic acid |
| Purity: | ≥98% (HPLC) |
GPR35 agonist; more potent than zaprinast (Cat. No. 0947)
| Chemical Name: | 4-[[2-[(2-Fluorophenyl)amino]-4-oxo-5(4H)-thiazolylidene]methyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Highly potent and selective GPR84 agonist
| Chemical Name: | 3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide |
| Purity: | ≥98% (HPLC) |
