YE 120
Tocris Bioscience, part of Bio-Techne | Catalog # 4457
GPR35 agonist
Product Description
YE 120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). Also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM).Product Specifications
Molecular Weight
330.17
Formula
C16H9Cl2N3O
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile
CAS Number
383124-82-1
PubChem ID
12138435
InChI Key
RSWZFAPYKOARNG-UHFFFAOYSA-N
SMILES
CC(C(C2=CC=C(Cl)C(Cl)=C2)(C)O1)=C(C#N)/C1=C(C#N)\C#N
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.02 | 100 |
Preparing Stock Solutions
for YE 120
The following data is based on the product molecular weight 330.17
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.03 mL | 15.14 mL | 30.29 mL |
| 5 mM | 0.61 mL | 3.03 mL | 6.06 mL |
| 10 mM | 0.30 mL | 1.51 mL | 3.03 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.61 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for YE 120
For research use only
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