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Nectin-2/CD112 Products

Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.

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290 results for "Nectin-2/CD112" in Products

290 results for "Nectin-2/CD112" in Products

Nectin-2/CD112 Products

Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.

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Reactivity: Mouse
Details: Rat IgG2a Monoclonal Clone #829038
Applications: Flow, CyTOF-ready
Detection of Nectin-2/CD112 antibody in C2C12 Mouse Cell Line antibody by Flow Cytometry.
Source: HEK293
Accession #: NP_002847.1
Applications: BA
Recombinant Human Nectin-2/CD112 Fc Chimera Protein Bioactivity

Control for use with Human and Non-Human Primate Nectin-2/CD112 Simple Plex Cartridge Kit

Applications: Ctrl, Simple Plex

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #JG39-64
Applications: IHC, WB, ICC/IF, Flow
Western Blot: Nectin-2/CD112 Antibody (JG39-64) [NBP2-76852]
(7)

Analyzed by SEC-MALS

Source: NS0
Accession #: NP_002847
Applications: Bind
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Mouse
Details: Rat IgG2a Monoclonal Clone #829038
Applications: Flow
Detection of Nectin-2/CD112 antibody in C2C12 Mouse Cell Line antibody by Flow Cytometry.
Reactivity: Mouse
Details: Rat IgG2a Monoclonal Clone #829038
Applications: Flow
Detection of Nectin-2/CD112 antibody in C2C12 Mouse Cell Line antibody by Flow Cytometry.

Simple Plex Non-Human Primate Nectin-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex
(3)
Reactivity: Mouse
Details: Rat IgG2a Monoclonal Clone #829038
Applications: Flow

Biotinylated

Source: CHO
Accession #: NP_002847.1
Applications: BA
(2)

Biotinylated

Source: HEK293
Accession #: NP_002847.1
Applications: BA
(2)
Source: CHO
Accession #: XP_005589607.1
Applications: BA
Recombinant Cynomolgus Monkey Nectin-2/CD112 Fc Protein Binding Activity
(2)
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