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LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
50 results for "LIGHT/TNFSF14" in Products
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
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LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
50 results for "LIGHT/TNFSF14" in Products
BA
| Source : | NS0 |
| Accession # : | O43557 |
| Applications : | Bioactivity |
ELISA
| Sensitivity : | 16.5 pg/mL |
| Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Applications : | ELISA |
BA
| Source : | NS0 |
| Accession # : | Q9QYH9 |
| Applications : | Bioactivity |
WB, ELISA, IHC, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, ELISA, Immunohistochemistry, Western Blot |
Flow, CyTOF-ready
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry |
Flow
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | Flow Cytometry |
Catalog #:
BAF664
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB6643
Flow, CyTOF-ready, Neut
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2323C |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
Catalog #:
FAB17942N
Flow
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Catalog #:
MAB6642
ELISA
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115515R |
| Applications : | ELISA |
Catalog #:
MAB17943
Flow, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #906909 |
| Applications : | CyTOF-ready, Flow Cytometry |
Flow
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | Flow Cytometry |
Catalog #:
MAB1794
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #261639 |
| Applications : | Western Blot |
Catalog #:
DY1794-05
ELISA
| Assay Range : | 250 - 16,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB17942
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17942R
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Catalog #:
BAF1794
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
FAB664G
Flow
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | Flow Cytometry |
Catalog #:
FAB664T
Flow
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17943N
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #906909 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17943G
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #906909 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17943T
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #906909 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17942U
Flow
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
