
LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
52 results for "LIGHT/TNFSF14" in Products
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LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
52 results for "LIGHT/TNFSF14" in Products
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Source : | NS0 |
Accession # : | O43557 |
Applications : | Bioactivity |
Sensitivity : | 16.5 pg/mL |
Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
Applications : | ELISA |
Source : | NS0 |
Accession # : | Q9QYH9 |
Applications : | Bioactivity |
Simple Plex Cartridge Kit for quantitation of LIGHT. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2323C |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, ELISA, Immunohistochemistry, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #885310 |
Applications : | Flow Cytometry |
Assay Range : | 62.5 - 4,000 pg/mL |
Applications : | ELISA |
Clone 115520 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #115520 |
Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #885310 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #115515R |
Applications : | ELISA |
Clone 115520 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #115520 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #885310 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #885310 |
Applications : | Flow Cytometry |
Clone 115520 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #115520 |
Applications : | Flow Cytometry |
Assay Range : | 250 - 16,000 pg/mL |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #906909 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #885310 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #261639 |
Applications : | Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2323C |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |