Sign In / Register
LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
52 results for "LIGHT/TNFSF14" in Products
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
LIGHT/TNFSF14 Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
52 results for "LIGHT/TNFSF14" in Products
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
BA
| Source : | NS0 |
| Accession # : | O43557 |
| Applications : | Bioactivity |
ELISA
| Sensitivity : | 16.5 pg/mL |
| Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Applications : | ELISA |
BA
| Source : | NS0 |
| Accession # : | Q9QYH9 |
| Applications : | Bioactivity |
Catalog #:
SPCKB-PS-000142
Simple Plex Cartridge Kit for quantitation of LIGHT. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Catalog #:
FAB6643N
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2323C |
| Applications : | Flow Cytometry |
WB, ELISA, IHC, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, ELISA, Immunohistochemistry, Western Blot |
Catalog #:
FAB17942R
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
Flow, CyTOF-ready
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry |
Catalog #:
BAF664
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Catalog #:
BAF1794
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
MAB17942
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Catalog #:
MAB6642
ELISA
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115515R |
| Applications : | ELISA |
Catalog #:
FAB664G
Flow
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17942G
Flow
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17942N
Flow
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Flow
Clone 115520 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #115520 |
| Applications : | Flow Cytometry |
Catalog #:
DY1794-05
ELISA
| Assay Range : | 250 - 16,000 pg/mL |
| Applications : | ELISA |
Catalog #:
FAB17943N
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #906909 |
| Applications : | Flow Cytometry |
Catalog #:
FAB17942V
Flow
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #885310 |
| Applications : | Flow Cytometry |
Catalog #:
MAB1794
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #261639 |
| Applications : | Western Blot |
Catalog #:
MAB6643
Flow, CyTOF-ready, Neut
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2323C |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
