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LIGHT/TNFSF14 Products

LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.

50 results for "LIGHT/TNFSF14" in Products

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LIGHT/TNFSF14 Products

LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.

50 results for "LIGHT/TNFSF14" in Products

WB, ELISA, IHC, Neut
Flow, CyTOF-ready

Clone 115520 was used by HLDA to establish CD designation

Clone 115520 was used by HLDA to establish CD designation

Catalog #: BAF664
WB
Flow, CyTOF-ready, Neut

Recombinant Monoclonal Antibody.

Catalog #: FAB17942N
Flow

Recombinant Monoclonal Antibody

ELISA

Recombinant Monoclonal Antibody.

Flow, CyTOF-ready

Clone 115520 was used by HLDA to establish CD designation

WB
ELISA
Flow

Recombinant Monoclonal Antibody.

Flow

Recombinant Monoclonal Antibody.

Catalog #: BAF1794
WB
Catalog #: FAB664G
Flow

Clone 115520 was used by HLDA to establish CD designation

Catalog #: FAB664T
Flow

Clone 115520 was used by HLDA to establish CD designation

Flow
Catalog #: FAB17943G
Flow
Catalog #: FAB17943T
Flow
Catalog #: FAB17942U
Flow

Recombinant Monoclonal Antibody

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