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LIFR alpha Products

Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts. The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIFR alpha, also known as LIFR beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex.

29 results for "LIFR alpha" in Products

LIFR alpha Products

Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts. The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIFR alpha, also known as LIFR beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex.

29 results for "LIFR alpha" in Products

Catalog #: BAF249
WB
BA
WB, Flow, CyTOF-ready
Catalog #: FAB249G
Flow
Catalog #: FAB249N
Flow
Flow, CyTOF-ready
Catalog #: 5990-LR
BA
Catalog #: FAB249V
Flow

An Improved rh LIF Ra is Available! The new protein has ~3 fold better activity and enhanced purity!

Flow
Catalog #: RDC1977
BA
BA
Catalog #: FAB249R
Flow
Catalog #: FAB249U
Flow
Catalog #: FAB249S
Flow
Catalog #: FAB5990G
Flow
Flow
Catalog #: FAB249T
Flow
Catalog #: FAB5990U
Flow
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