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LIFR alpha Products

Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIFR alpha, also known as LIFR beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex.

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215 results for "LIFR alpha" in Products

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LIFR alpha Products

Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIFR alpha, also known as LIFR beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex.

Products:

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215 results for "LIFR alpha" in Products

WB, Flow, CyTOF-ready
Flow
WB
BA
Flow, CyTOF-ready
BA
BA
Flow
Flow
Catalog #: FAB249V
Flow
Catalog #: FAB5990U
Flow
Catalog #: FAB5990G
Flow
Catalog #: FAB249N
Flow
Catalog #: FAB249T
Flow
Catalog #: FAB249G
Flow
Catalog #: FAB249S
Flow
Catalog #: FAB249R
Flow
Catalog #: FAB249U
Flow
Catalog #: FAB5990S
Flow
Catalog #: FAB5990V
Flow
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