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7 results for "Lck Antibodies" in Products

Lck Antibodies

Lck (p56lck) is a member of the Src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and over-expressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene. Lck behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show over-expression of Lck, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers.

Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #33D196
Applications:
WB
Novus Antibodies
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