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JAK Kinase Inhibitors Products
18 results for "JAK Kinase Inhibitors" in Products
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JAK Kinase Inhibitors Products
18 results for "JAK Kinase Inhibitors" in Products
Catalog #:
7064
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
| Alternate Names : | INCB018424 |
| Chemical Name : | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile |
| Purity : | ≥98% (HPLC) |
Catalog #:
6577
Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
| Alternate Names : | JAK inhibitor I |
| Chemical Name : | 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one |
| Purity : | ≥98% (HPLC) |
Catalog #:
7048
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
| Chemical Name : | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile phosphate |
| Purity : | ≥98% (HPLC) |
Catalog #:
7222
Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2
| Alternate Names : | INCB 28050 |
| Chemical Name : | 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile |
| Purity : | ≥98% (HPLC) |
Potent JAK inhibitor
| Alternate Names : | Tofacitinib citrate |
| Chemical Name : | (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate |
| Purity : | ≥99% (HPLC) |
Potent, selective JAK3 inhibitor
| Chemical Name : | 3-benzylisopropylamino-1-naphthalen-2-yl-propan-1-one hydrochloride |
| Purity : | ≥99% (HPLC) |
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
| Alternate Names : | CEP-701 |
| Chemical Name : | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity : | ≥99% (HPLC) |
Catalog #:
4221
Potent JAK3 inhibitor. Also inhibits GSK-3β and PKC
| Alternate Names : | NIBR3049 |
| Chemical Name : | 3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Purity : | ≥98% (HPLC) |
Catalog #:
3035
JAK2/STAT3 signaling pathway inhibitor
| Chemical Name : | (1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester |
| Purity : | ≥99% (HPLC) |
Catalog #:
6125
Potent TYK2 inhibitor
| Chemical Name : | 2-Chloro-4-cyano-6-fluoro-N-[2-[[[(1R,2R)-2-fluorocyclopropyl]carbonyl]amino]-4-pyridinyl]benzamide |
| Purity : | ≥98% (HPLC) |
Potent, selective JAK3 inhibitor
| Chemical Name : | 1-(2-Naphthalenyl)-2-propen-1-one |
| Purity : | ≥98% (HPLC) |
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
| Alternate Names : | Tyrphostin AG 490 |
| Chemical Name : | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide |
| Purity : | ≥99% (HPLC) |
Potent Mnk2 inhibitor
| Chemical Name : | (9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide |
| Purity : | ≥96% (HPLC) |
Potent and selective JAK3 inhibitor
| Chemical Name : | 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malate |
| Purity : | ≥98% (HPLC) |
Catalog #:
3115
JAK3 kinase inhibitor. Also inhibits EGFR
| Chemical Name : | 2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol |
| Purity : | ≥99% (HPLC) |
Catalog #:
5617
Potent and selective JAK2 inhibitor; antiangiogenic
| Chemical Name : | 5-Chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidine-2,4-diamine |
| Purity : | ≥98% (HPLC) |
Selective inhibitor of STAT3/JAK2 signaling
| Alternate Names : | Elatericin B, JSI 124 |
| Chemical Name : | (9β,10α,16α,23E)-2,16,20,25-Tetrahydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione |
| Purity : | ≥95% (HPLC) |
Catalog #:
4580
JAK2 inhibitor
| Chemical Name : | N,N-Diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2-propanamine dihydrochloride |
