Integrin alpha V/CD51 Products
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.
46 results for "Integrin alpha V/CD51" in Products
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Integrin alpha V/CD51 Products
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.
46 results for "Integrin alpha V/CD51" in Products
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P5H9 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #273210 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Knockout Validated, Simple Western, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #273210 |
Applications : | Flow Cytometry |
Potent and selective inhibitor of integrins αvβ3 and αvβ5
Alternate Names : | EMD121974 |
Purity : | ≥95% (HPLC) |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P2W7 |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P5H9 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #23C6 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P2W7 |
Applications : | Flow Cytometry |
Potent αv integrin inhibitor
Chemical Name : | 3-[[2,5-Dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-L-alanine |
Purity : | ≥97% (HPLC) |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #23C6 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #23C6 |
Applications : | Flow Cytometry |
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
Purity : | ≥95% (HPLC) |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #273210 |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P5H9 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #23C6 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P2W7 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #273210 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #P5H9 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #23C6 |
Applications : | Flow Cytometry |