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IL-3: Proteins and Enzymes

Interleukin-3 (IL-3) is a secreted cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. It also regulates the activation of mature mast cells, basophils, eosinophils, and macrophages. It is produced by activated T cells, thymic epithelial cells, activated mast cells, keratinocytes, neurons, and astrocytes.

IL-3 signals through a receptor complex that contains IL-3 R alpha/CD123 and the common beta chain which is also a component of the receptors for IL-5 and GM-CSF. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils, and various myeloid leukemic cells. Human IL-3 does not show activity on mouse cells.

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10 results for "IL-3 Proteins and Enzymes" in Products

10 results for "IL-3 Proteins and Enzymes" in Products

IL-3: Proteins and Enzymes

Interleukin-3 (IL-3) is a secreted cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. It also regulates the activation of mature mast cells, basophils, eosinophils, and macrophages. It is produced by activated T cells, thymic epithelial cells, activated mast cells, keratinocytes, neurons, and astrocytes.

IL-3 signals through a receptor complex that contains IL-3 R alpha/CD123 and the common beta chain which is also a component of the receptors for IL-5 and GM-CSF. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils, and various myeloid leukemic cells. Human IL-3 does not show activity on mouse cells.

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Analyzed by SEC-MALS

Source: E. coli
Accession #: AAC08706
Applications: BA
(3)

Analyzed by SEC-MALS

Source: E. coli
Accession #: NP_034686
Applications: BA
(3)

Animal-Free.

Source: E. coli
Accession #: AAC08706.1
Applications: BA
Recombinant Human IL-3 GMP Protein Bioactivity
(3)
Applications: WB, ELISA
ELISA: Recombinant Porcine IL-3 Protein [NBP3-11061]
Source: E. coli
Accession #: AAC08706.1
Applications: BA
(3)
Source: E. coli
Accession #: AAC08706.1
Applications: BA
(3)

Intended for preclinical researchers who may transition to GMP IL-3 for their clinical work

Source: E. coli
Accession #: AAC08706.1
Applications: BA
R&D Systems Animal-Free Recombinant Proteins
Source: E. coli
Accession #: P97688
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Applications: PAGE, Bioactivity
SDS-PAGE: Recombinant Canine IL-3 Protein [NBP2-34898]
Applications: PAGE, Bioactivity
HPLC: Recombinant Rhesus Macaque IL-3 Protein [NBP2-35308]
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