Is there a mass to unit conversion for Recombinant Mouse IL-3 Protein (Catalog # 403-ML & 403-ML/CF)?

Name: Recombinant Mouse IL-3 Protein
Brand: R&D Systems
SKU: 403-ML
Rating: 4 (6 reviews)

We have developed an approximate mass to unit conversion factor for Recombinant Mouse IL-3 Protein (Catalog # 403-ML & 403-ML/CF) based on testing against WHO Standard (NIBSC code: 91/662). In this testing, we found a relative conversion of 1 ug of cytokine = 1.7 x 105 Units. This information can be found in our Unit Conversion Table: https://www.rndsystems.com/resources/technical-information/unit-conversion-tablePlease note this information is for reference purposes only and is not routinely tested.

Recombinant Mouse IL-3 Protein

R&D Systems, Inc. a Bio-Techne Brand

Catalog # 403-ML

Citations (164)

(6)

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Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	NP_034686
Applications:	Bioactivity

View Full Technical Details for Recombinant Mouse IL-3 Protein

Product Specifications for Recombinant Mouse IL-3 Protein

Source	E. coli-derived mouse IL-3 protein Asp33-Cys166, with an N-terminal Met
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Asp33
Predicted Molecular Mass	15 kDa
Activity	Measured in a cell proliferation assay using NFS‑60 mouse myelogenous leukemia lymphoblast cells. Holmes, K.L. et al. (1985) Proc. Natl. Acad. Sci. USA 82:6687. The ED₅₀ for this effect is 20-100 pg/mL.

Scientific Data Examples for Recombinant Mouse IL-3 Protein

	Recombinant Mouse IL-3 Protein Bioactivity Recombinant Mouse IL-3 (Catalog # 403-ML) stimulates cell proliferation of the NFS-60 mouse myelogenous leukemia lymphoblast cell line. The ED₅₀ for this effect is 20-100 pg/mL.
	Recombinant Mouse IL-3 Protein SDS-PAGE 1 μg/lane of Recombinant Mouse IL-3 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 15 kDa.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

403-ML

Carrier

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

403-ML/CF

Carrier Free

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute at 100 μg/mL in sterile PBS.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-3

Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages. Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, burst promoting activity, multi-colony stimulating factor, thy-1 inducing factor and WEHI-3 growth factor. In addition to activated T cells, other cell types such as human thymic epithelial cells, activated mouse mast cells, mouse keratinocytes and neurons/astrocytes can also produce IL-3. At the amino acid sequence level, mature human and mouse IL-3 share only 29% sequence identity. Consistent with this lack of homology, IL-3 activity is highly species-specific and human IL-3 does not show activity on mouse cells.

IL-3 exerts its biological activities through binding to specific cell surface receptors. The high affinity receptor responsible for IL-3 signaling is composed of alpha and beta subunits. The IL-3R alpha is a member of the cytokine receptor super family and binds IL-3 with low affinity. Two distinct beta subunits, AIC2A ( beta _IL-3) and AIC2B ( beta _c) are present in mouse cells. beta _IL-3 also binds IL-3 with low affinity and forms a high affinity receptor with the alpha subunit. The beta _c subunits does not bind any cytokine but forms functional high affinity receptors with the alpha subunit of the IL-3, IL-5 and GM-CSF receptors. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils and various myeloid leukemic cells.

Item	Value
References	Yokota, T. et al., 1984, Proc. Natl. Acad. Sci. USA 81:1070. Fung, M.C. et al., 1984, Nature 307:233. Miyatake, S. et al., 1985, Proc. Natl. Acad. Sci. USA 82:316.
Long Name	Interleukin 3
Entrez Gene IDs	3562 (Human); 16187 (Mouse); 24495 (Rat)
Alternate Names	Hematopoietic growth factor, IL-3, IL-3MGC79398, IL3, MCGF, MCGFMGC79399, MULTI-CSF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell stimulating factor, P-cell-stimulating factor, interleukin 3 (colony-stimulating factor, multiple), interleukin-3, mast-cell growth factor, multilineage-colony-stimulating factor

Citations for Recombinant Mouse IL-3 Protein (164)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse IL-3 Protein include:

Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BE Thacker et al. (2022), Multiplex genome editing of mammalian cells for producing recombinant heparin Metabolic engineering, 0(0).
PMID: 35038554
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Li et al. (2022), A functional genomic approach to actionable gene fusions for precision oncology Science Advances, 8(6):eabm2382.
PMID: 35138907
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Q Zhang et al. (2022), Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis JCI Insight, 7(3).
PMID: 35132955
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KMZ Savill et al. (2022), Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors Nature Communications, 13(1):2057.
PMID: 35440108
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Fujita et al. (2022), IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis Cells, 11(9).
PMID: 35563758
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

T Doke et al. (2022), Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis Nature Immunology, 0(0).
PMID: 35552540
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Hayashi et al. (2022), MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Cell Reports, 39(6):110805.
PMID: 35545056
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HJ Shin et al. (2022), Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTDï¿½1067 Oncogene, 12(1):10853.
PMID: 35760980
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JA Iskarpatyo et al. (2022), Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter Cell Reports, 40(13):111346.
PMID: 36170813
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Chakrabort et al. (2022), Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo Cell Reports, 40(12):111360.
PMID: 36130519
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

L Rani et al. (2022), IL-3 regulates the differentiation of pathogenic Th17 cells European Journal of Immunology, 0(0).
PMID: 36074916
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

X Liu et al. (2022), IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia Embo Molecular Medicine, 0(0):e15631.
PMID: 36453131
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

JF Fu et al. (2021), HOXA11 plays critical roles in disease progression and response to cytarabine in AML Oncology reports, 46(1).
PMID: 34080665
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

RA Cardenas et al. (2021), SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis The Journal of Biological Chemistry, 296(0):100268.
PMID: 33837726
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

N Ohashi et al. (2021), GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS Scientific Reports, 11(1):12803.
PMID: 34140581
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

D Kashima et al. (2021), Evolution of KIPPIS as a versatile platform for evaluating intracellularly functional peptide aptamers Scientific Reports, 11(1):11758.
PMID: 34083659
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

X Wang et al. (2021), MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF Cell Death and Differentiation, 0(0).
PMID: 34079078
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Z Wang et al. (2021), A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction European Journal of Medicinal Chemistry, 220(0):113452.
PMID: 33906046
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KR Thomas et al. (2021), Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice Leukemia, 0(0).
PMID: 34193976
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Kongkrongt et al. (2021), Rational design of heterodimeric receptors capable of activating target signaling molecules Scientific Reports, 11(1):16809.
PMID: 34413422
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Takashima et al. (2021), Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells Scientific Reports, 11(1):1520.
PMID: 33452355
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HZ Guo et al. (2021), Leukemic progenitor cells enable immunosuppression and post-chemotherapy relapse via IL-36-inflammatory monocyte axis Science Advances, 7(41):eabg4167.
PMID: 34623912
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

F Herbst et al. (2021), The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision Leukemia, 0(0).
PMID: 34021250
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Song et al. (2021), Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance Leukemia, 0(0).
PMID: 34007045
Species: Mouse

Applications: Cell Culture

H Seo et al. (2020), Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line Cell. Mol. Immunol., 0(0).
PMID: 32457406
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

A Jandke et al. (2020), Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial &gamma&delta T cell compartments Nat Commun, 11(1):3769.
PMID: 32724083
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

SG Rudd et al. (2020), Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy EMBO Mol Med, 12(3):e10419.
PMID: 31950591
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

S Kreutmair et al. (2020), Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model Leukemia, 0(0).
PMID: 32203142
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JH Kang et al. (2020), Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division Nat Commun, 11(1):4983.
PMID: 33020492
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Girotra et al. (2020), In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro Int J Mol Sci, 21(21).
PMID: 33153113
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Huang et al. (2020), Covalent inhibition of NSD1 histone methyltransferase Nat. Chem. Biol., 0(0).
PMID: 32868895
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

JM Inclan-Ric et al. (2020), Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition Nat. Immunol., 0(0).
PMID: 32807943
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

D Gonçalves et al. (2020), In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia PLoS ONE, 15(12):e0244368.
PMID: 33370388
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Yoshimi et al. (2020), Genetic basis for iMCD-TAFRO Oncogene, 0(0).
PMID: 32051554
Species: Transgenic Mouse
Sample Types: Spheroid
Applications: Bioassay

AE Engler et al. (2020), Airway-Associated Macrophages in Homeostasis and Repair Cell Reports, 33(13):108553.
PMID: 33378665
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Hong et al. (2020), Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System Biomedicines, 8(12).
PMID: 33317212
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

JM Inclan-Ric et al. (2020), Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition Nat. Immunol., 0(0).
PMID: 32807943
Species: Mouse
Sample Types: Transfected Whole Cells
Applications: Bioassay

A Ní Chealla et al. (2020), Chemical synthesis of a sulfated d-glucosamine library and evaluation of cell proliferation capabilities Carbohydr. Res., 495(0):108085.
PMID: 32807354
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

GY Lee et al. (2019), Age-related differences in the bone marrow stem cell niche generate specialized microenvironments for the distinct regulation of normal hematopoietic and leukemia stem cells Sci Rep, 9(1):1007.
PMID: 30700727
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Czechowicz et al. (2019), Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation Nat Commun, 10(1):617.
PMID: 30728354
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JT Hsieh et al. (2019), Japanese encephalitis virus neuropenetrance is driven by mast cell chymase Nat Commun, 10(1):706.
PMID: 30742008
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

N Funk et al. (2019), The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4 Sci Rep, 9(1):4515.
PMID: 30872638
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

F Ribezzo et al. (2019), Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome Leukemia, 0(0).
PMID: 30651631
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Li et al. (2019), Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC Haematologica, 0(0).
PMID: 30975912
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Magadmi et al. (2019), Secretion of Mast Cell Inflammatory Mediators Is Enhanced by CADM1-Dependent Adhesion to Sensory Neurons Front Cell Neurosci, 13(0):262.
PMID: 31275114
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A Yoshimi et al. (2019), Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis Nature, 0(0).
PMID: 31578525
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MM de Rezende et al. (2019), Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation Cell. Signal., 67(0):109507.
PMID: 31857239
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

T Fukushima et al. (2019), Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium Cell Rep, 29(12):4144-4158.e7.
PMID: 31851939
Species: Human
Sample Types: Whole Cells
Applications: BioassayCell

T Kawase et al. (2019), Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Oncotarget, 10(58):6111-6123.
PMID: 31692922
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

YL Chang et al. (2019), Lipocalin 2: A New Antimicrobial in Mast Cells Int J Mol Sci, 20(10).
PMID: 31091692
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Papaspyrop et al. (2018), RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73 Nat Commun, 9(1):424.
PMID: 29382819
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Heshmati et al. (2018), The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation Sci Rep, 8(1):11202.
PMID: 30046127
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JP Robichaux et al. (2018), Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer Nat. Med., 0(0).
PMID: 29686424
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HT Fang et al. (2018), Global H3.3 dynamic deposition defines its bimodal role in cell fate transition Nat Commun, 9(1):1537.
PMID: 29670118
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

P Herbener et al. (2018), Functional relevance of in vivo half antibody exchange of an IgG4 therapeutic antibody-drug conjugate PLoS ONE, 13(4):e0195823.
PMID: 29672587
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Berndt et al. (2018), Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach Stem Cell Res Ther, 9(1):117.
PMID: 29703251
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Rasheed et al. (2018), Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells J Am Heart Assoc, 7(10).
PMID: 29739800
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

X Jin et al. (2018), Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice Haematologica, 0(0).
PMID: 29903757
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Reitz et al. (2018), Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory Sci Rep, 8(1):8636.
PMID: 29872093
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Wang et al. (2018), The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia Oncogene, 0(0).
PMID: 29459712
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BA Gutierrez et al. (2018), Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells J. Biol. Chem., 0(0).
PMID: 29599294
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Kono et al. (2018), Biological and epidemiological evidence of anti-allergic effects of traditional Japanese food ume (Prunus mume) Sci Rep, 8(1):11638.
PMID: 30076416
P Wünsche et al. (2018), Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs Cell Stem Cell, 23(1):132-146.e9.
PMID: 29979988
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Saika et al. (2018), ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGF? pathway genes through histone deacetylation Sci Rep, 8(1):15873.
PMID: 30367089
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IZ Uras et al. (2018), Therapeutic Vulnerabilities in FLT3-Mutant AML Unmasked by Palbociclib Int J Mol Sci, 19(12).
PMID: 30544932
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

E Sanchez et al. (2018), Syntaxin 3, but not Syntaxin 4, is required for mast cell regulated exocytosis, where it plays a primary role mediating compound exocytosis J. Biol. Chem., 0(0).
PMID: 30563839
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Z He et al. (2018), Mast cells are essential intermediaries in regulating IL-33/ST2 signaling for an immune network favorable to mucosal healing in experimentally inflamed colons Cell Death Dis, 9(12):1173.
PMID: 30518915
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

RJ Kimmerling et al. (2018), Linking single-cell measurements of mass, growth rate, and gene expression Genome Biol., 19(1):207.
PMID: 30482222
Species: Mouse

Applications: Cell Culture

Y Kimizuka et al. (2018), Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response J. Immunol., 0(0).
PMID: 30420435
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JE Choi et al. (2018), Botulinum toxin blocks mast cells and prevents rosacea like inflammation J. Dermatol. Sci., 0(0).
PMID: 30658871
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation

R Ramachandr et al. (2018), A Study and Review of Effects of Botulinum Toxins on Mast Cell Dependent and Independent Pruritus Toxins (Basel), 10(4).
PMID: 29570628
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MQ Wentink et al. (2018), A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys Vaccine, 0(0).
PMID: 29519591
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

S Xu et al. (2018), E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells Circ. Res., 0(0).
PMID: 29358228
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

M Bachmann et al. (2018), An unexpected protective role of low affinity allergen-specific IgG via the inhibitory receptor Fc?RIIb J. Allergy Clin. Immunol., 0(0).
PMID: 29391255
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Nagase et al. (2018), Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation J. Exp. Med., 0(0).
PMID: 29643185
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

I Aguiñiga-S et al. (2017), Chemical analyses and in vitro and in vivo toxicity of fruit methanol extract of Sechium edule var. nigrum spinosum Pharm Biol, 55(1):1638-1645.
PMID: 28427292
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

N Okamoto et al. (2017), Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex J. Biol. Chem., 0(0).
PMID: 28754693
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

N Nagata et al. (2017), Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D2 PLoS ONE, 12(4):e0175452.
PMID: 28394950
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

LD Goldstein et al. (2017), Massively parallel nanowell-based single-cell gene expression profiling BMC Genomics, 18(1):519.
PMID: 28687070
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Lu et al. (2017), Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer Cancer Res., 0(0).
PMID: 28512244
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HJ Lee et al. (2017), Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation Cell Rep, 20(3):721-736.
PMID: 28723573
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SY Kim et al. (2017), Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion Oncotarget, 8(9):15014-15022.
PMID: 28122360
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KZ Oben et al. (2017), Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1) PLoS ONE, 12(1):e0169767.
PMID: 28081176
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

X Jiang et al. (2017), Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia Nat Commun, 8(1):2099.
PMID: 29235481
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Itoh-Nakad et al. (2017), A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors Cell Rep, 18(10):2401-2414.
PMID: 28273455
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Q Bernard et al. (2017), Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice Parasit Vectors, 10(1):313.
PMID: 28655322
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

DA Casolari et al. (2017), A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm Sci Rep, 7(1):2467.
PMID: 28550306
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Han et al. (2017), Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis PLoS ONE, 12(1):e0166014.
PMID: 28135282
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

AJ Lee et al. (2017), Lipopolysaccharide/TLR4 Stimulates IL-13 Production through a MyD88-BLT2-Linked Cascade in Mast Cells, Potentially Contributing to the Allergic Response J. Immunol., 0(0).
PMID: 28600286
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Mast cell desensitization inhibits calcium flux and aberrantly remodels actin J Clin Invest, 0(0).
PMID: 27669462
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins PLoS ONE, 11(11):e0164003.
PMID: 27806040
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HJ Park et al. (2016), iNKT Cells Are Responsible for the Apoptotic Reduction of Basophils That Mediate Th2 Immune Responses Elicited by Papain in Mice Following ?PGA Stimulation PLoS ONE, 11(4):e0152189.
PMID: 27049954
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors Nat Commun, 7(0):13396.
PMID: 27869129
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells Cancer Res., 0(0).
PMID: 27879269
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis Oncogene, 0(0).
PMID: 27869160
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Quantitative trait gene Slit2 positively regulates murine hematopoietic stem cell numbers Sci Rep, 6(0):31412.
PMID: 27503415
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Arna E Andrews (2016), Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis J. Immunol., 0(0).
PMID: 27807194
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2 Cancer Discov, 0(0).
PMID: 27630126
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yoichiroh Hosokawa (2016), Time-Course Statistical Evaluation of Intercellular Adhesion Maturation by Femtosecond Laser Impulse Biophys. J., 111(10):2255-2262.
PMID: 27851947
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis PLoS ONE, 11(5):e0154630.
PMID: 27159398
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer Br J Cancer, 0(0).
PMID: 27575850
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency Stem Cell Reports, 0(0).
PMID: 27453007
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Di Marco B et al. (2016), Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific ?? T Cell Compartments Cell, 167(1):203-218.e17.
PMID: 27641500
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Miyawaki K et al. (2015), CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor. Stem Cells, 33(3):976-87.
PMID: 25446279
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lee S et al. (2015), Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages. PLoS ONE, 10(7):e0132329.
PMID: 26147219
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang H et al. (2015), HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1. J Immunol, 194(11):5375-87.
PMID: 25895533
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Schumacher A et al. (2015), Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy. J Hematol Oncol, 8(0):64.
PMID: 26054961
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang F et al. (2015), Mouse Resistin (mRetn): cloning, expression and purification in Escherichia coli and the potential regulative effects on murine bone marrow hematopoiesis. BMC Biotechnol, 15(0):105.
PMID: 26572487
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang L et al. (2015), The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy. Leukemia, 29(6):1320-30.
PMID: 25655194
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mierzejewska K et al. (2015), Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells. Stem Cells Dev, 24(8):927-37.
PMID: 25607657
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gonzalez Roldan N et al. (2015), CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice. Eur J Immunol, 46(2):432-9.
PMID: 26564814
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Huan J et al. (2015), Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes. Leukemia, 29(12):2285-95.
PMID: 26108689
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kim P et al. (2015), Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. J Exp Med, 212(5):633-48.
PMID: 25870201
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Illert et al. (2015), Grb10 is involved in BCR-ABL-positive leukemia in mice. Leukemia, 29(4):858-68.
PMID: 25249015
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

O Iijima et al. (2015), Prevention of Lethal Murine Hypophosphatasia by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells Hum. Gene Ther, 26(12):801-12.
PMID: 26467745
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Richter R et al. (2014), Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev, 23(16):1959-74.
PMID: 24708339
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Bakocevic N et al. (2014), CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections. Eur J Immunol, 44(6):1823-34.
PMID: 24610714
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nagareddy P et al. (2014), Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metab, 19(5):821-35.
PMID: 24807222
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Luviano A et al. (2014), Antineoplastic activity of rinvanil and phenylacetylrinvanil in leukaemia cell lines. Oncol Lett, 7(5):1651-1656.
PMID: 24765194
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nakahara F et al. (2014), Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells. Blood, 123(25):3932-42.
PMID: 24825862
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kim E et al. (2014), Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 xi chain on T cells, abrogating alloreactive T cells. Immunology, 142(3):421-30.
PMID: 24527810
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Muench M et al. (2014), The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny. PLoS ONE, 9(5):e97312.
PMID: 24819392
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yu et al. (2014), Targeting oncoprotein stability overcomes drug resistance caused by FLT3 kinase domain mutations. PLoS ONE, 9(5):e97116.
PMID: 24849514
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Weston W et al. (2014), Dynamic equilibrium of heterogeneous and interconvertible multipotent hematopoietic cell subsets. Sci Rep, 4(0):5199.
PMID: 24903657
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Morimoto et al. (2014), Prostaglandin E2-EP3 signaling induces inflammatory swelling by mast cell activation. J Immunol, 192(3):1130-7.
PMID: 24342806
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hiragun T et al. (2014), Establishment of a mast cell line, NCL-2, without Kit mutation, derived from NC mouse bone marrow. FEBS Open Bio, 4(0):342-6.
PMID: 24918047
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zhang H et al. (2014), Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells, 32(1):191-203.
PMID: 24022884
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Bettini M et al. (2014), TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. J Immunol, 193(2):571-9.
PMID: 24943217
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Luyten A et al. (2014), Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells. Genes Dev, 28(16):1827-39.
PMID: 25128499
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Liu X et al. (2014), The DNA binding property of PML/RARA but not the integrity of PML nuclear bodies is indispensable for leukemic transformation. PLoS ONE, 9(8):e104906.
PMID: 25119106
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mabe et al. (2014), Detecting protein-protein interactions based on kinase-mediated growth induction of mammalian cells. Sci Rep, 4(0):6127.
PMID: 25135216
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Boettcher S et al. (2014), Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood, 124(9):1393-403.
PMID: 24990886
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wallington-Beddoe C et al. (2014), Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression. Cancer Res, 74(10):2803-15.
PMID: 24686171
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reber L et al. (2014), Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism. J Immunol, 192(4):1847-54.
PMID: 24453258
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chen H et al. (2014), A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment. Sci Rep, 4(0):6222.
PMID: 25164363
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lee F et al. (2014), The effects of CAMPATH-1H on cell viability do not correlate to the CD52 density on the cell surface. PLoS ONE, 9(7):e103254.
PMID: 25050704
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gautier E et al. (2013), HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders. J Exp Med, 210(2):339-53.
PMID: 23319699
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Siracusa M et al. (2013), Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity, 39(6):1158-70.
PMID: 24332033
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pope et al. (2013), Establishment of a cell-type-specific genetic network by the mediator complex component Med1. Mol Cell Biol, 33(10):1938-55.
PMID: 23459945
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Jeong H et al. (2013), The critical role of mast cell-derived hypoxia-inducible factor-1alpha in human and mice melanoma growth. Int J Cancer, 132(11):2492-501.
PMID: 23161568
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Huang W et al. (2013), Fas-associated phosphatase 1 (Fap1) influences betacatenin activity in myeloid progenitor cells expressing the Bcr-abl oncogene. J Biol Chem, 288(18):12766-76.
PMID: 23519466
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shah et al. (2013), The leukemia-associated Mll-Ell oncoprotein induces fibroblast growth factor 2 (Fgf2)-dependent cytokine hypersensitivity in myeloid progenitor cells. J Biol Chem, 288(45):32490-505.
PMID: 24089521
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Gao et al. (2013), Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo. J Exp Med, 210(13):2833-42.
PMID: 24297994
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pereira C et al. (2013), Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell, 13(2):205-18.
PMID: 23770078
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sandig H et al. (2013), IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation. Eur J Immunol, 43(4):979-88.
PMID: 23404570
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yamamizu K et al. (2013), Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports, 1(6):545-59.
PMID: 24371809
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2012), Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A, 109(25):9971-6.
PMID: 22665806
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Matsushita H et al. (2011), Differential but competitive binding of Nogo protein and class i major histocompatibility complex (MHCI) to the PIR-B ectodomain provides an inhibition of cells. J. Biol. Chem., 286(29):25739-47.
PMID: 21636572
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kinzfogl J et al. (2011), Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. Blood, 118(3):565-75.
PMID: 21628410
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bustany S et al. (2011), Cyclin D1 regulates p27(Kip1) stability in B cells. Cell. Signal., 23(1):171-9.
PMID: 20837141
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Kayamuro H et al. (2010), Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J. Virol., 84(24):12703-12.
PMID: 20881038
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bokhoven M et al. (2009), Insertional gene activation by lentiviral and gammaretroviral vectors. J. Virol., 83(1):283-94.
PMID: 18945765
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Perrigoue JG et al. (2009), MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat. Immunol., 10(7):697-705.
PMID: 19465906
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yamaguchi Y et al. (2007), IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J. Immunol., 179(10):7128-36.
PMID: 17982105
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zhu J et al. (2007), Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood, 109(9):3706-12.
PMID: 17227831
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Yuan W et al. (2007), Commonly dysregulated genes in murine APL cells. Blood, 109(3):961-70.
PMID: 17008535
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bao YC et al. (2006), Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors. J. Cell Biol., 175(6):937-46.
PMID: 17178910
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yilmaz OH et al. (2005), SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood, 107(3):924-30.
PMID: 16219798
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dikov MM et al. (2005), Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation. J. Immunol., 174(1):215-22.
PMID: 15611243
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cox GN et al. (2004), Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor/immunoglobulin fusion protein. Exp. Hematol., 32(5):441-9.
PMID: 15145212
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Armstrong SA et al. (2003), Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification. Cancer Cell, 3(2):173-83.
PMID: 12620411
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gyotoku E et al. (2001), The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice. Arch. Dermatol. Res., 293(10):508-14.
PMID: 11820727
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Liu F et al. (1997), Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation. Blood, 90(7):2583-90.
PMID: 9326224
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reitz M et al. (0), Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory. Sci Re8(1):8636.
PMID: 29872093

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Customer Reviews for Recombinant Mouse IL-3 Protein (6)

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Recombinant Mouse IL-3 Protein

Name: Anonymous

Application: In vitro bioactivity in cell culture

Verified Customer | Posted 11/20/2021
Name: Anonymous

Application: Immunoassay Standard

Verified Customer | Posted 06/15/2018
Name: Anonymous

Application: Cell Adhesion

Verified Customer | Posted 05/14/2018
Name: Anonymous

Verified Customer | Posted 04/26/2017

I used IL-3 to culture my Ba/F3 cells. With IL3, they are growing well and viable.
Recombinant Mouse IL-3 Protein

Name: Marco Ramos

Application: CellProlif

Reason for Rating: Expensive but worth the money

Verified Customer | Posted 04/04/2017
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Application: Cell migration/motility

Verified Customer | Posted 05/18/2016

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FAQs for Recombinant Mouse IL-3 Protein

Is there a mass to unit conversion for Recombinant Mouse IL-3 Protein (Catalog # 403-ML & 403-ML/CF)?

We have developed an approximate mass to unit conversion factor for Recombinant Mouse IL-3 Protein (Catalog # 403-ML & 403-ML/CF) based on testing against WHO Standard (NIBSC code: 91/662). In this testing, we found a relative conversion of 1 ug of cytokine = 1.7 x 10⁵ Units. This information can be found in our Unit Conversion Table: https://www.bio-techne.com/resources/technical-information/unit-conversion-tablePlease note this information is for reference purposes only and is not routinely tested.

Recombinant Mouse IL-3 Protein

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Citations for Recombinant Mouse IL-3 Protein (164)

Customer Reviews for Recombinant Mouse IL-3 Protein (6)

Recombinant Mouse IL-3 Protein

Recombinant Mouse IL-3 Protein

Recombinant Mouse IL-3 Protein

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