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510 results for "IL-23" in Products

IL-23 Products

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

Reactivity:
Human
Assay Range:
39-2500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Human IL-23 ELISA Standard Curve
(2)
Reactivity:
Human
Source:
Sf 21 (baculovirus)
Accession #:
P29460 (p40) & AAG37232 (p19)
Applications:
Bioactivity
Reactivity:
Mouse
Assay Range:
15.6-1000 pg/mL (Cell Culture Supernates, Serum, Heparin Plasma)
Applications:
ELISA
Mouse IL-23 ELISA Standard Curve
(2)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
IL‑17 Secretion Induced by IL‑23 and Neutralization by Human IL‑23 Antibody.
(2)
Reactivity:
Mouse
Assay Range:
39.1-2500 pg/mL
Applications:
ELISA
Mouse IL-23 ELISA Standard Curve
Reactivity:
Human, Feline
Details:
Sheep IgG Polyclonal
Applications:
WB
Detection of Human IL-23 p19 antibody by Western Blot.
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
IL‑17 secretion Induced by IL‑23 and Neutralization by Mouse IL‑23 Antibody.
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF, IP
Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-77257]
(11)
Reactivity:
Human
Assay Range:
125-8000 pg/mL
Applications:
ELISA
Human IL-23 ELISA Standard Curve

Analyzed by SEC-MALS.

Reactivity:
Mouse
Source:
HEK293
Accession #:
P43432.1 (p40) & Q9EQ14.1 (p19)
Applications:
Bioactivity
(3)

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Rabbit IgG2B Monoclonal Clone #1193B
Applications:
WB, B/N
Detection of Human IL-23 p19 antibody by Western Blot.
(2)
Reactivity:
Rat
Source:
Sf 21 (baculovirus)
Accession #:
NP_072133 (p40) & NP_569094 (p19)
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF
Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-76697]
(5)

Analyzed by SEC-MALS

Reactivity:
Human
Source:
CHO
Applications:
Bioactivity
(2)
Reactivity:
Human, Canine
Details:
Sheep IgG Polyclonal
Applications:
WB
Detection of Human and Canine IL-23 p19 antibody by Western Blot.

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #JE38-99
Applications:
IHC, WB
IL-23 Antibody (JE38-99)
(4)

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG1 Monoclonal
Applications:
ELISA, Flow, Func
IL-23A/IL-23 P19 Antibody (risankizumab) - Humanized
Reactivity:
Human
Reactivity:
Human
Reactivity:
Human
Source:
Baculovirus
Applications:
PAGE
SDS-PAGE: Recombinant Human IL-23 His Protein [NBP2-80388]
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