IL-21 Products
IL-21 (Interleukin-21) is member of the family of cytokines that utilize the common gamma chain as a receptor subunit. This subunit is also a component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex of the common gamma chain and the IL-21-specific IL-21 R. IL-21 supports Tfh cell development, immunoglobulin affinity maturation, plasma cell differentiation, B cell memory responses, and the migration of dendritic cells to draining lymph nodes. It costimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization. It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells. In addition, IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.
459 results for "IL-21" in Products
459 results for "IL-21" in Products
IL-21 Products
IL-21 (Interleukin-21) is member of the family of cytokines that utilize the common gamma chain as a receptor subunit. This subunit is also a component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex of the common gamma chain and the IL-21-specific IL-21 R. IL-21 supports Tfh cell development, immunoglobulin affinity maturation, plasma cell differentiation, B cell memory responses, and the migration of dendritic cells to draining lymph nodes. It costimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization. It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells. In addition, IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.
| Source: | E. coli |
| Accession #: | Q9HBE4.3 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Source: | E. coli |
| Accession #: | Q9HBE4.3 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q9ES17.1 |
| Applications: | BA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | NULL |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #149204 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Source: | E. coli |
| Accession #: | Q9HBE4.3 |
| Applications: | BA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | Q9HBE4.3 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q9HBE4.3 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #14k5H3 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: IL-21 Antibody (14k5H3) [NBP2-27336]](https://resources.bio-techne.com/images/products/IL-21-Antibody-14k5H3-Western-Blot-NBP2-27336-img0002.jpg "Western Blot: IL-21 Antibody (14k5H3) [NBP2-27336]")
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #149204 |
| Applications: | ICFlow |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #149204 |
| Applications: | ICFlow |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #1004614 |
| Applications: | ELISA |