IL-11 Products
Interleukin-11, also known as AGIF, is a pleiotropic cytokine in the IL-6 family, which also includes LIF, CNTF, Oncostatin M, Cardiotrophin-1, IL-27, and IL-31. It is secreted by osteoblasts, synoviocytes, fibroblasts, chondrocytes, intestinal myofibroblasts, and trophoblasts. It is found in the plasma mainly during inflammation, and is considered to be primarily anti-inflammatory. It stimulates hematopoiesis and thrombopoiesis, regulates macrophage differentiation, and confers mucosal protection in the intestine. It has also been found to enhance T cell polarization toward Th2, promote B cell IgG production, increase osteoclast bone absorption, protect endothelial cells from oxidative stress, and regulate epithelial proliferation and apoptosis. IL-11 signals through a receptor complex that contains IL-11 R alpha and gp130. A soluble form of IL-11 R alpha can bind IL-11 and either form a signaling complex with gp130 on the cell surface or inhibit cell surface IL-11 R alpha/gp130 signaling.
34 results for "IL-11" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
IL-11 Products
Interleukin-11, also known as AGIF, is a pleiotropic cytokine in the IL-6 family, which also includes LIF, CNTF, Oncostatin M, Cardiotrophin-1, IL-27, and IL-31. It is secreted by osteoblasts, synoviocytes, fibroblasts, chondrocytes, intestinal myofibroblasts, and trophoblasts. It is found in the plasma mainly during inflammation, and is considered to be primarily anti-inflammatory. It stimulates hematopoiesis and thrombopoiesis, regulates macrophage differentiation, and confers mucosal protection in the intestine. It has also been found to enhance T cell polarization toward Th2, promote B cell IgG production, increase osteoclast bone absorption, protect endothelial cells from oxidative stress, and regulate epithelial proliferation and apoptosis. IL-11 signals through a receptor complex that contains IL-11 R alpha and gp130. A soluble form of IL-11 R alpha can bind IL-11 and either form a signaling complex with gp130 on the cell surface or inhibit cell surface IL-11 R alpha/gp130 signaling.
34 results for "IL-11" in Products
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
Source : | Sf 9 (baculovirus) |
Accession # : | P20809.1 |
Applications : | Bioactivity |
Source : | Sf 21 (baculovirus) |
Accession # : | P20809.1 |
Applications : | Bioactivity |
Sensitivity : | 8 pg/mL |
Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates) 31.2 - 2,000 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #22626 |
Applications : | Block/Neutralize, Western Blot |
Source : | CHO |
Accession # : | P20809.1 |
Applications : | Bioactivity |
Assay Range : | 125 - 8,000 pg/mL |
Applications : | ELISA |
Assay Range : | 31.2 - 2,000 pg/mL |
Applications : | ELISA |
Source : | E. coli |
Accession # : | P47873 |
Applications : | Bioactivity |
Simple Plex Human IL-11 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #22626R |
Applications : | Block/Neutralize, Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #188520 |
Applications : | Block/Neutralize, Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #188507 |
Applications : | ELISA Capture |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Western Blot |