
IL-1 RI Products
IL-1 RI, also known as the type 1 IL-1 receptor and CD121a, is a transmembrane protein in the Toll/IL-1 R (TIR) superfamily. IL-1 RI binds the pleiotropic cytokines IL-1 alpha and IL-1 beta, plus the IL-1 receptor antagonist (IL-1 Ra). Signal transduction requires complex formation with IL-1 R AcP/IL-1 R3. This complex recruits the adaptor protein MyD88, to initiate signaling in the NF kappa B pathway. IL-1 RI is expressed predominantly by T cells, fibroblasts, and endothelial cells and mediates acute phase inflammatory responses including fever.
36 results for "IL-1 RI" in Products
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IL-1 RI Products
IL-1 RI, also known as the type 1 IL-1 receptor and CD121a, is a transmembrane protein in the Toll/IL-1 R (TIR) superfamily. IL-1 RI binds the pleiotropic cytokines IL-1 alpha and IL-1 beta, plus the IL-1 receptor antagonist (IL-1 Ra). Signal transduction requires complex formation with IL-1 R AcP/IL-1 R3. This complex recruits the adaptor protein MyD88, to initiate signaling in the NF kappa B pathway. IL-1 RI is expressed predominantly by T cells, fibroblasts, and endothelial cells and mediates acute phase inflammatory responses including fever.
36 results for "IL-1 RI" in Products
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Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #35730 |
Applications : | ELISA Capture, Western Blot |
Source : | NS0 |
Accession # : | P14778 |
Applications : | Bioactivity |
Potent, selective human type I IL-1 receptor antagonist
Purity : | ≥95% (HPLC) |
Assay Range : | 125 - 8,000 pg/mL |
Applications : | ELISA |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Source : | HEK293 |
Accession # : | P14778.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #129301 |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Hamster IgG Clone #JAMA147 |
Applications : | Block/Neutralize |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #129304 |
Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Source : | NS0 |
Accession # : | P13504 |
Applications : | Bioactivity |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #732210 |
Applications : | Western Blot |
Assay Range : | 93.8 - 6,000 pg/mL |
Applications : | ELISA |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #129304 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #129304 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #129304 |
Applications : | Flow Cytometry |