Human IL-1 RI (NP_000868) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1258
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-1 RI
IL-1 RI, also known as the type 1 IL-1 receptor and CD121a, is a transmembrane protein in the Toll/IL-1 R (TIR) superfamily. IL-1 RI binds the pleiotropic cytokines IL-1 alpha and IL-1 beta, plus the IL-1 receptor antagonist (IL-1 Ra). Signal transduction requires complex formation with IL-1 R AcP/IL-1 R3. This complex recruits the adaptor protein MyD88, to initiate signaling in the NF kappa B pathway. IL-1 RI is expressed predominantly by T cells, fibroblasts, and endothelial cells and mediates acute phase inflammatory responses including fever.
Long Name
Interleukin 1 Receptor I
Alternate Names
CD121a, IL-1RI, IL1R1, IL1RI
Gene Symbol
IL1R1
UniProt
Additional IL-1 RI Products
Product Documents for Human IL-1 RI (NP_000868) VersaClone cDNA
Product Specific Notices for Human IL-1 RI (NP_000868) VersaClone cDNA
For research use only
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