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IL-1 RI: Proteins and Enzymes
IL-1 RI, also known as the type 1 IL-1 receptor and CD121a, is a transmembrane protein in the Toll/IL-1 R (TIR) superfamily. IL-1 RI binds the pleiotropic cytokines IL-1 alpha and IL-1 beta, plus the IL-1 receptor antagonist (IL-1 Ra). Signal transduction requires complex formation with IL-1 R AcP/IL-1 R3. This complex recruits the adaptor protein MyD88, to initiate signaling in the NF kappa B pathway. IL-1 RI is expressed predominantly by T cells, fibroblasts, and endothelial cells and mediates acute phase inflammatory responses including fever.
5 results for "IL-1 RI Proteins and Enzymes" in Products
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IL-1 RI: Proteins and Enzymes
IL-1 RI, also known as the type 1 IL-1 receptor and CD121a, is a transmembrane protein in the Toll/IL-1 R (TIR) superfamily. IL-1 RI binds the pleiotropic cytokines IL-1 alpha and IL-1 beta, plus the IL-1 receptor antagonist (IL-1 Ra). Signal transduction requires complex formation with IL-1 R AcP/IL-1 R3. This complex recruits the adaptor protein MyD88, to initiate signaling in the NF kappa B pathway. IL-1 RI is expressed predominantly by T cells, fibroblasts, and endothelial cells and mediates acute phase inflammatory responses including fever.
5 results for "IL-1 RI Proteins and Enzymes" in Products
BA
| Source : | NS0 |
| Accession # : | P14778 |
| Applications : | Bioactivity |
Catalog #:
11085-RI
BA
| Source : | HEK293 |
| Accession # : | P14778.1 |
| Applications : | Bioactivity |
Catalog #:
771-MR
BA
| Source : | NS0 |
| Accession # : | P13504 |
| Applications : | Bioactivity |
Catalog #:
AVI11319
BA
Biotinylated
| Source : | HEK293 |
| Accession # : | P14778.1 |
| Applications : | Bioactivity |
Catalog #:
4895-MR
BA
| Source : | NS0 |
| Accession # : | Q02955 |
| Applications : | Bioactivity |
