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7 results for "IKK beta" in Products
IKK beta Products
The classical active IKK complex, composed of IKK alpha, IKK beta, and two forms of processed IKK gamma, phosphorylates and inactivates IkB, resulting in the release and nuclear translocation of active NFkB. The regulatory IKK gamma is required for activation of the IKK complex. IKK epsilon is an IKK-related kinase with 30% structural homology to IKK alpha and beta, and is present in a subset of IKK complexes.
Potent, selective inhibitor of IKKβ
Chemical Name:
2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide
Purity:
≥97%
Novel IKK2-selective inhibitor
Chemical Name:
N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridinecarboxamide dihydrochloride
Purity:
≥98%
Selective IKKα and IKKβ inhibitor
Chemical Name:
2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile
Purity:
≥97%
Selective inhibitor of IKK
Chemical Name:
N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride
Purity:
≥98%
Selective allosteric inhibitor of IKK; anti-inflammatory
Chemical Name:
N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine hydrochloride
Purity:
≥98%
Inhibitor of IKKβ; also exhibits antibacterial activity
Chemical Name:
N-[3,5-Bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide
Purity:
≥98%
Potent and selective IKKβ inhibitor
Chemical Name:
8-[[[5-Chloro-2-[3,4-dimethyl-3,4-bis(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxamide
Purity:
≥98%
