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8 results for "GluR5/GRIK1 Small Molecules and Peptides" in Products

GluR5/GRIK1: Small Molecules and Peptides

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA ...

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Kainate agonist; excitant and neurotoxin

Chemical Name: (2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
Purity: ≥98% (HPLC)
Kainate agonist; excitant and neurotoxin

Broad spectrum glutamatergic antagonist

Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid
Purity: ≥98% (HPLC)
Broad spectrum glutamatergic antagonist

Competitive non-NMDA iGluR antagonist

Alternate Names: MPQX
Chemical Name: [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
Purity: ≥98% (HPLC)
Competitive non-NMDA iGluR antagonist

Potent kainate antagonist; displays selectivity for GluK1-containing receptors

Chemical Name: (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione
Purity: ≥98% (HPLC)
Potent kainate antagonist; displays selectivity for GluK1-containing receptors

Potent and selective GluK1 kainate agonist

Chemical Name: (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid
Purity: ≥98% (HPLC)
Potent and selective GluK1 kainate agonist

Potent and selective kainate antagonist; active enantiomer of UBP 296 (Cat. No. 2078)

Chemical Name: (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
Purity: ≥98% (HPLC)
Potent and selective kainate antagonist; active enantiomer of UBP 296 (Cat. No. 2078)

Potent and selective kainate antagonist; selective for GluK1-containing receptors

Chemical Name: (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
Purity: ≥98% (HPLC)
Potent and selective kainate antagonist; selective for GluK1-containing receptors

Non-competitive non-NMDA iGluR antagonist

Alternate Names: GYKI 53773,LY 300164
Chemical Name: (8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine
Purity: ≥98% (HPLC)
Non-competitive non-NMDA iGluR antagonist
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