7 results for "Gap Channel Blockers Small Molecules and Peptides" in Products
Gap Channel Blockers: Small Molecules and Peptides
Gap channels (also known as gap junctions) are specalized cell-cell contacts between almost all eukaryotic cells that provide direct intracellular communication. Generally, gap channels allow the passive diffusion of molecules up to 1 kDa which includes nutrients, small metabolites (e.g. glucose), ions (K+, Ca2+) and second messengers (IP3, cAMP and cGMP).
Gap channels allow electrical and biochemical coupling between cells and in excitable tissues, such as neurons and the heart, enables the ...
Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal
| Chemical Name: | (αS)-rel-α-(2R)-2-Piperidinyl-2,3-bis(trifluoromethyl-4-quinolinemethanol hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective gap junction blocker
| Purity: | ≥95% (HPLC) |
Cx43 hemichannel blocker
| Purity: | ≥95% (HPLC) |
Control peptide for TAT-Gap19
| Purity: | ≥95% (HPLC) |
Cx43 hemichannel blocker
| Purity: | ≥95% (HPLC) |
Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
| Purity: | ≥95% (HPLC) |
Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase
| Chemical Name: | (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium |
| Purity: | ≥98% (HPLC) |