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Focal Adhesion Kinase Inhibitors Products

FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.

6 results for "Focal Adhesion Kinase Inhibitors" in Products

Focal Adhesion Kinase Inhibitors Products

FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.

6 results for "Focal Adhesion Kinase Inhibitors" in Products

Dual FAK/PYK2 inhibitor

Potent and selective FAK inhibitor

Potent FAK inhibitor; orally bioavailable

Potent and selective FAK and Pyk2 inhibitor

Selective FAK inhibitor

Potent focal adhesion kinase (FAK) inhibitor

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