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PF 573228

Tocris Bioscience a Bio-Techne Brand

PF 573228 | CAS No. 869288-64-2 | Potent and selective FAK inhibitor
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Key Product Details

Description: Potent and selective FAK inhibitor
Chemical Name: 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
Purity: ≥98% (HPLC)
Molecular Weight: 491.49

Citations for PF 573228 (48)

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Customer Reviews for PF 573228 (3)

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  • Cell cultures with ECM proteins, integrin blockade and In vitro drug treatments
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: rat astroglioma C6 cells
    pharmacological antagonists of FAK for 4 h before RNA or protein isolation. FAK antagonists were PF573228
    PF 573228 Serum 3239
  • Inhibitor of FAK and effects on E0771 extracellular flux
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: E0771
    Extracellular flux analysis (Seahorse experiments) of breast cancer cells. 5uM dose used for 48hrs
  • Inhibiting FAK expression in 2D and 3D cell culture
    Name: Aesha Desai
    Species: Human
    Effective at inhibiting FAK expression when used in 2D (monolayer) and 3D (spheroid/microtissue) cell culture

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Product Documents for PF 573228

Certificate of Analysis

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