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FGFR4 Products
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
25 results for "FGFR4" in Products
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FGFR4 Products
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
25 results for "FGFR4" in Products
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Source : | NS0 |
| Accession # : | P22455 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Source : | NS0 |
| Accession # : | Q03142 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Assay Range : | 156 - 10,000 pg/mL |
| Applications : | ELISA |
| Source : | CHO |
| Accession # : | P22455.2 |
| Applications : | Bioactivity |
Biotinylated
| Source : | HEK293 |
| Accession # : | P22455.2 |
| Applications : | Bioactivity |
Clone 137114 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #137114 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #240929 |
| Applications : | Flow Cytometry |
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
Potent, irreversible FGFR inhibitor
| Chemical Name : | N-(3-((3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-(4-(diethylamino)butylamino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide |
| Purity : | ≥96% (HPLC) |
