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FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
32 results for "FGF-21" in Products
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FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
32 results for "FGF-21" in Products
BA
| Source : | NS0 |
| Accession # : | Q9JJN1 |
| Applications : | Bioactivity |
Catalog #:
SPCK-PANEL
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Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ELISA
| Sensitivity : | 8.69 pg/mL |
| Assay Range : | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Catalog #:
SPCKB-PS-000401
Simple Plex Cartridge Kit for quantitation of FGF-21. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Catalog #:
SPCKB-MP-006323
Simple Plex Cartridge Kit for quantitation of FGF-21. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
ELISA
| Sensitivity : | 13.4 pg/mL |
| Assay Range : | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
BA
| Source : | E. coli |
| Accession # : | Q9NSA1 |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
ELISA
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
Catalog #:
BAF2539
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
WB, ELISA
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA, Western Blot |
Catalog #:
MAB25371
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #315901 |
| Applications : | Western Blot |
Catalog #:
MAB25373
Neut
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Goat IgG2b Clone #40020A |
| Applications : | Block/Neutralize |
Catalog #:
MAB25372
CyTOF-ready, ICC, ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #461804 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Catalog #:
MAB2537
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #315914 |
| Applications : | Western Blot |
Catalog #:
MAB25374
ELISA
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #461801 |
| Applications : | ELISA |
Catalog #:
IC25372G
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #461804 |
| Applications : | Flow Cytometry |
