FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
310 results for "FGF-21" in Products
310 results for "FGF-21" in Products
FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
| Sensitivity: | 13.4 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Sensitivity: | 8.69 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Source: | E. coli |
| Accession #: | Q9NSA1 |
| Applications: | BA |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Applications: | Simple Plex |
Simple Plex Human FGF-21 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Simple Plex Mouse/Rat FGF-21 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | Q9JJN1 |
| Applications: | BA |
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
Control for use with Human FGF-21 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #OTI2F10 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: FGF-21 Antibody (OTI2F10) [NBP2-00645]](https://resources.bio-techne.com/images/products/FGF21-Antibody-2F10-Western-Blot-NBP2-00645-img0002.jpg "Western Blot: FGF-21 Antibody (OTI2F10) [NBP2-00645]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315901 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #OTI2F10 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
![Western Blot: FGF-21 Antibody (OTI2F10)Azide and BSA Free [NBP2-71815]](https://resources.bio-techne.com/images/products/FGF-21-Antibody-OTI2F10-Azide-and-BSA-Free-Western-Blot-NBP2-71815-img0001.jpg "Western Blot: FGF-21 Antibody (OTI2F10)Azide and BSA Free [NBP2-71815]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #461801 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #315914 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | CyTOF-ready, ICC, ICFlow |
