Endothelin ETA Receptor Antagonists Products
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
2 results for "Endothelin ETA Receptor Antagonists" in Products
2 results for "Endothelin ETA Receptor Antagonists" in Products
Endothelin ETA Receptor Antagonists Products
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
| Chemical Name: | (αS)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid |
| Purity: | ≥98% (HPLC) |
